Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial.
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| Title: | Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial. |
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| Authors: | Moskowitz A; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts., Huang DT; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.; Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Hou PC; Division of Emergency Critical Care Medicine, Department of Emergency Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Gong J; Department of Emergency Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York., Doshi PB; Department of Emergency Medicine, McGovern Medical School at UTHealth, Houston, Texas.; Division of Critical Care, Department of Internal Medicine, McGovern Medical School at UTHealth, Houston, Texas., Grossestreuer AV; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts., Andersen LW; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Research Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Denmark.; Prehospital Emergency Medical Services, Central Denmark Region, Denmark., Ngo L; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts., Sherwin RL; Sinai Grace Hospital, Department of Emergency Medicine, Wayne State University School of Medicine, Detroit, Michigan., Berg KM; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts., Chase M; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts., Cocchi MN; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Division of Critical Care, Department of Anesthesia Critical Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts., McCannon JB; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mount Auburn Hospital, Cambridge, Massachusetts., Hershey M; Division of Critical Care Medicine, South Shore Hospital, Weymouth, Massachusetts., Hilewitz A; Division of Pulmonary, Critical Care, and Sleep Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York., Korotun M; Division of Pulmonary, Critical Care, and Sleep Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York., Becker LB; Department of Emergency Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York., Otero RM; Beaumont Hospital, Department of Emergency Medicine, Oakland University William Beaumont School of Medicine, Beaumont, Michigan., Uduman J; Division of Pulmonary and Critical Care Medicine, Division of Nephrology and Hypertension, Henry Ford Hospital, Detroit, Michigan., Sen A; Department of Critical Care Medicine, Mayo Clinic, Phoenix, Arizona., Donnino MW; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts. |
| Corporate Authors: | ACTS Clinical Trial Investigators |
| Source: | JAMA [JAMA] 2020 Aug 18; Vol. 324 (7), pp. 642-650. |
| Publication Type: | Journal Article; Multicenter Study; Randomized Controlled Trial |
| Journal Info: | Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 32809003 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Moskowitz+A%22">Moskowitz A</searchLink>; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Huang+DT%22">Huang DT</searchLink>; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.; Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Hou+PC%22">Hou PC</searchLink>; Division of Emergency Critical Care Medicine, Department of Emergency Medicine, Brigham and Women's Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Gong+J%22">Gong J</searchLink>; Department of Emergency Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York.<br /><searchLink fieldCode="AU" term="%22Doshi+PB%22">Doshi PB</searchLink>; Department of Emergency Medicine, McGovern Medical School at UTHealth, Houston, Texas.; Division of Critical Care, Department of Internal Medicine, McGovern Medical School at UTHealth, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Grossestreuer+AV%22">Grossestreuer AV</searchLink>; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Andersen+LW%22">Andersen LW</searchLink>; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Research Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Denmark.; Prehospital Emergency Medical Services, Central Denmark Region, Denmark.<br /><searchLink fieldCode="AU" term="%22Ngo+L%22">Ngo L</searchLink>; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Sherwin+RL%22">Sherwin RL</searchLink>; Sinai Grace Hospital, Department of Emergency Medicine, Wayne State University School of Medicine, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Berg+KM%22">Berg KM</searchLink>; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Chase+M%22">Chase M</searchLink>; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Cocchi+MN%22">Cocchi MN</searchLink>; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Division of Critical Care, Department of Anesthesia Critical Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22McCannon+JB%22">McCannon JB</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mount Auburn Hospital, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Hershey+M%22">Hershey M</searchLink>; Division of Critical Care Medicine, South Shore Hospital, Weymouth, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Hilewitz+A%22">Hilewitz A</searchLink>; Division of Pulmonary, Critical Care, and Sleep Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York.<br /><searchLink fieldCode="AU" term="%22Korotun+M%22">Korotun M</searchLink>; Division of Pulmonary, Critical Care, and Sleep Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York.<br /><searchLink fieldCode="AU" term="%22Becker+LB%22">Becker LB</searchLink>; Department of Emergency Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York.<br /><searchLink fieldCode="AU" term="%22Otero+RM%22">Otero RM</searchLink>; Beaumont Hospital, Department of Emergency Medicine, Oakland University William Beaumont School of Medicine, Beaumont, Michigan.<br /><searchLink fieldCode="AU" term="%22Uduman+J%22">Uduman J</searchLink>; Division of Pulmonary and Critical Care Medicine, Division of Nephrology and Hypertension, Henry Ford Hospital, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Sen+A%22">Sen A</searchLink>; Department of Critical Care Medicine, Mayo Clinic, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Donnino+MW%22">Donnino MW</searchLink>; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Center for Resuscitation Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22ACTS+Clinical+Trial+Investigators%22">ACTS Clinical Trial Investigators</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227501160%22">JAMA</searchLink> [JAMA] 2020 Aug 18; Vol. 324 (7), pp. 642-650. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7501160 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-3598 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200987484%22">00987484 </searchLink><i>NLM ISO Abbreviation: </i>JAMA <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=32809003 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1001/jama.2020.11946 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 642 Titles: – TitleFull: Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Moskowitz A – PersonEntity: Name: NameFull: Huang DT – PersonEntity: Name: NameFull: Hou PC – PersonEntity: Name: NameFull: Gong J – PersonEntity: Name: NameFull: Doshi PB – PersonEntity: Name: NameFull: Grossestreuer AV – PersonEntity: Name: NameFull: Andersen LW – PersonEntity: Name: NameFull: Ngo L – PersonEntity: Name: NameFull: Sherwin RL – PersonEntity: Name: NameFull: Berg KM – PersonEntity: Name: NameFull: Chase M – PersonEntity: Name: NameFull: Cocchi MN – PersonEntity: Name: NameFull: McCannon JB – PersonEntity: Name: NameFull: Hershey M – PersonEntity: Name: NameFull: Hilewitz A – PersonEntity: Name: NameFull: Korotun M – PersonEntity: Name: NameFull: Becker LB – PersonEntity: Name: NameFull: Otero RM – PersonEntity: Name: NameFull: Uduman J – PersonEntity: Name: NameFull: Sen A – PersonEntity: Name: NameFull: Donnino MW IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 08 Text: 2020 Aug 18 Type: published Y: 2020 Identifiers: – Type: issn-electronic Value: 1538-3598 Numbering: – Type: volume Value: 324 – Type: issue Value: 7 Titles: – TitleFull: JAMA Type: main |
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