Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer.
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| Title: | Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer. |
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| Authors: | Luszczak S; Molecular Diagnostics and Therapeutics Group, University College London, London, UK., Simpson BS; Molecular Diagnostics and Therapeutics Group, University College London, London, UK., Stopka-Farooqui U; Molecular Diagnostics and Therapeutics Group, University College London, London, UK., Sathyadevan VK; Molecular Diagnostics and Therapeutics Group, University College London, London, UK., Echeverria LMC; Molecular Diagnostics and Therapeutics Group, University College London, London, UK., Kumar C; Molecular Diagnostics and Therapeutics Group, University College London, London, UK., Costa H; Research Department of Pathology, University College London, London, UK., Haider A; Research Department of Pathology, University College London, London, UK., Freeman A; Research Department of Pathology, University College London, London, UK., Jameson C; Research Department of Pathology, University College London, London, UK., Ratynska M; Research Department of Pathology, University College London, London, UK., Ben-Salha I; Research Department of Pathology, University College London, London, UK., Sridhar A; Department of Uro-Oncology, UCLH NHS Foundation Trust, London, UK., Shaw G; Department of Uro-Oncology, UCLH NHS Foundation Trust, London, UK., Kelly JD; Department of Uro-Oncology, UCLH NHS Foundation Trust, London, UK., Pye H; Molecular Diagnostics and Therapeutics Group, University College London, London, UK., Gately KA; Trinity Translational Medicine Institute, St. James's Hospital Dublin, Dublin 8, Ireland., Whitaker HC; Molecular Diagnostics and Therapeutics Group, University College London, London, UK., Heavey S; Molecular Diagnostics and Therapeutics Group, University College London, London, UK. s.heavey@ucl.ac.uk. |
| Source: | Scientific reports [Sci Rep] 2020 Sep 01; Vol. 10 (1), pp. 14380. Date of Electronic Publication: 2020 Sep 01. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-020-71263-9 |
