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Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia.

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Title: Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia.
Authors: Autry RJ; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA., Paugh SW; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Carter R; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Shi L; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA., Liu J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Ferguson DC; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Lau CE; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Pediatric Oncology Education Program, St. Jude Children's Research Hospital, Memphis, TN, USA., Bonten EJ; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Yang W; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., McCorkle JR; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Beard JA; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Panetta JC; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Diedrich JD; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Crews KR; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Pei D; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA., Coke CJ; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Natarajan S; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Khatamian A; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Karol SE; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Comprehensive Cancer Center, St. Jude Children's Research Hospital, Memphis, TN, USA., Lopez-Lopez E; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Diouf B; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Smith C; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Gocho Y; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Hagiwara K; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Roberts KG; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Pounds S; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA., Kornblau SM; Department of Leukemia, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Stock W; Hematopoiesis and Hematological Malignancies Program, University of Chicago, Chicago, IL, USA., Paietta EM; Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, North Division, Bronx, NY, USA., Litzow MR; Division of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA., Inaba H; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Mullighan CG; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Jeha S; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Pui CH; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Cheng C; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA., Savic D; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Yu J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Gawad C; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Relling MV; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA., Yang JJ; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Evans WE; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA. William.Evans@stjude.org.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. William.Evans@stjude.org.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA. William.Evans@stjude.org.
Source: Nature cancer [Nat Cancer] 2020 Mar; Vol. 1 (3), pp. 329-344. Date of Electronic Publication: 2020 Mar 09.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Autry+RJ%22">Autry RJ</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Paugh+SW%22">Paugh SW</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Carter+R%22">Carter R</searchLink>; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Shi+L%22">Shi L</searchLink>; 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Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Yu+J%22">Yu J</searchLink>; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Gawad+C%22">Gawad C</searchLink>; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Relling+MV%22">Relling MV</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Yang+JJ%22">Yang JJ</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Evans+WE%22">Evans WE</searchLink>; Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN, USA. William.Evans@stjude.org.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. William.Evans@stjude.org.; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN, USA. William.Evans@stjude.org.
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              Value: 2662-1347
          Numbering:
            – Type: volume
              Value: 1
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Nature cancer
              Type: main
ResultId 1