Inhibition of IRF5 hyperactivation protects from lupus onset and severity.

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Title: Inhibition of IRF5 hyperactivation protects from lupus onset and severity.
Authors: Song S; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA., De S; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.; Rutgers Graduate School of Biomedical Sciences, Newark, New Jersey, USA., Nelson V; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA., Chopra S; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA., LaPan M; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA., Kampta K; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA., Sun S; Center for Molecular Innovation, Feinstein Institutes for Medical Research, Manhasset, New York, USA., He M; Center for Molecular Innovation, Feinstein Institutes for Medical Research, Manhasset, New York, USA., Thompson CD; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA., Li D; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA., Shih T; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA., Tan N; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA., Al-Abed Y; Center for Molecular Innovation, Feinstein Institutes for Medical Research, Manhasset, New York, USA., Capitle E; Division of Allergy, Immunology and Rheumatology, Rutgers New Jersey Medical School, Newark, New Jersey, USA., Aranow C; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA., Mackay M; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA., Clapp WL; Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida, USA., Barnes BJ; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.; Departments of Molecular Medicine and Pediatrics, Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2020 Dec 01; Vol. 130 (12), pp. 6700-6717.
Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhibition of IRF5 hyperactivation protects from lupus onset and severity.
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  Data: <searchLink fieldCode="AU" term="%22Song+S%22">Song S</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22De+S%22">De S</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.; Rutgers Graduate School of Biomedical Sciences, Newark, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+V%22">Nelson V</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22Chopra+S%22">Chopra S</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22LaPan+M%22">LaPan M</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22Kampta+K%22">Kampta K</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22Sun+S%22">Sun S</searchLink>; Center for Molecular Innovation, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22He+M%22">He M</searchLink>; Center for Molecular Innovation, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22Thompson+CD%22">Thompson CD</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22Shih+T%22">Shih T</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22Tan+N%22">Tan N</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22Al-Abed+Y%22">Al-Abed Y</searchLink>; Center for Molecular Innovation, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22Capitle+E%22">Capitle E</searchLink>; Division of Allergy, Immunology and Rheumatology, Rutgers New Jersey Medical School, Newark, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Aranow+C%22">Aranow C</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22Mackay+M%22">Mackay M</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.<br /><searchLink fieldCode="AU" term="%22Clapp+WL%22">Clapp WL</searchLink>; Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Barnes+BJ%22">Barnes BJ</searchLink>; Center for Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institutes for Medical Research, Manhasset, New York, USA.; Departments of Molecular Medicine and Pediatrics, Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2020 Dec 01; Vol. 130 (12), pp. 6700-6717.
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  Data: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
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        Value: 10.1172/JCI120288
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        Text: English
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      – TitleFull: Inhibition of IRF5 hyperactivation protects from lupus onset and severity.
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