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Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems.

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Title: Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems.
Authors: Justice AE; Department of Population Health Sciences, Geisinger, Danville, PA 17822, USA.; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Chittoor G; Department of Population Health Sciences, Geisinger, Danville, PA 17822, USA., Gondalia R; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Melton PE; School of Biomedical Science, Faculty of Health & Medical Sciences, The University of Western Australia, Perth, WA 6000, Australia.; School of Pharmacy & Biomedical Sciences, Faculty of Health Sciences, Curtin University, MRF Building, Perth, WA 6000, Australia.; Menzies Institute for Medical Research, College of Health & Medicine, University of Tasmania, Hobart, TA, 7000 Australia., Lim E; Department of Biostatistics, Boston University, Boston, MA 02118, USA., Grove ML; Human Genetics Center, Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Whitsel EA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Liu CT; Department of Biostatistics, Boston University, Boston, MA 02118, USA., Cupples LA; Department of Biostatistics, Boston University, Boston, MA 02118, USA.; Framingham Heart Study, Framingham, MA, 01701, USA., Fernandez-Rhodes L; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Biobehavioral Health, Pennsylvania State University, University Park, PA 16802, USA., Guan W; Division of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA., Bressler J; Human Genetics Center, Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Fornage M; Center for Human Genetics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.; Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA., Li Y; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Genetics, University of North Carolina at Chapel Hill, NC 27599, USA., Demerath E; Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, MN 55455, USA., Heard-Costa N; Framingham Heart Study, Framingham, MA, 01701, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, 02118, USA., Levy D; Population sciences branch, NHLBI Framingham Heart Study, Framingham, MA 01702, USA.; Department of Medicine, Boston University, Boston, MA 02118, USA., Stewart JD; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Baccarelli A; Laboratory of Environmental Epigenetics, Departments of Environmental Health Sciences & Epidemiology, Columbia University Mailman School of Public Health, New York, NY 10032, USA., Hou L; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University Chicago, Evanston, IL, USA., Conneely K; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA., Mori TA; Medical School, University of Western Australia, Perth, Australia., Beilin LJ; Medical School, University of Western Australia, Perth, Australia., Huang RC; Telethon Kids Institute, University of Western Australia, Perth, Australia., Gordon-Larsen P; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, NC 27599, USA.; Carolina Population Center, University of North Carolina at Chapel Hill, NC 27516, USA., Howard AG; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Carolina Population Center, University of North Carolina at Chapel Hill, NC 27516, USA., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Carolina Population Center, University of North Carolina at Chapel Hill, NC 27516, USA.
Source: Epigenomics [Epigenomics] 2020 Sep; Vol. 12 (17), pp. 1483-1499. Date of Electronic Publication: 2020 Sep 09.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101519720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-192X (Electronic) Linking ISSN: 1750192X NLM ISO Abbreviation: Epigenomics Subsets: MEDLINE
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  Data: Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems.
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  Data: <searchLink fieldCode="AU" term="%22Justice+AE%22">Justice AE</searchLink>; Department of Population Health Sciences, Geisinger, Danville, PA 17822, USA.; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Chittoor+G%22">Chittoor G</searchLink>; Department of Population Health Sciences, Geisinger, Danville, PA 17822, USA.<br /><searchLink fieldCode="AU" term="%22Gondalia+R%22">Gondalia R</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Melton+PE%22">Melton PE</searchLink>; School of Biomedical Science, Faculty of Health & Medical Sciences, The University of Western Australia, Perth, WA 6000, Australia.; School of Pharmacy & Biomedical Sciences, Faculty of Health Sciences, Curtin University, MRF Building, Perth, WA 6000, Australia.; Menzies Institute for Medical Research, College of Health & Medicine, University of Tasmania, Hobart, TA, 7000 Australia.<br /><searchLink fieldCode="AU" term="%22Lim+E%22">Lim E</searchLink>; Department of Biostatistics, Boston University, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Grove+ML%22">Grove ML</searchLink>; Human Genetics Center, Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Whitsel+EA%22">Whitsel EA</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Liu+CT%22">Liu CT</searchLink>; Department of Biostatistics, Boston University, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Cupples+LA%22">Cupples LA</searchLink>; Department of Biostatistics, Boston University, Boston, MA 02118, USA.; Framingham Heart Study, Framingham, MA, 01701, USA.<br /><searchLink fieldCode="AU" term="%22Fernandez-Rhodes+L%22">Fernandez-Rhodes L</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Biobehavioral Health, Pennsylvania State University, University Park, PA 16802, USA.<br /><searchLink fieldCode="AU" term="%22Guan+W%22">Guan W</searchLink>; Division of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Bressler+J%22">Bressler J</searchLink>; Human Genetics Center, Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Fornage+M%22">Fornage M</searchLink>; Center for Human Genetics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.; Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Boerwinkle+E%22">Boerwinkle E</searchLink>; Human Genetics Center, Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Genetics, University of North Carolina at Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Demerath+E%22">Demerath E</searchLink>; Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Heard-Costa+N%22">Heard-Costa N</searchLink>; Framingham Heart Study, Framingham, MA, 01701, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, 02118, USA.<br /><searchLink fieldCode="AU" term="%22Levy+D%22">Levy D</searchLink>; Population sciences branch, NHLBI Framingham Heart Study, Framingham, MA 01702, USA.; Department of Medicine, Boston University, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Stewart+JD%22">Stewart JD</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Baccarelli+A%22">Baccarelli A</searchLink>; Laboratory of Environmental Epigenetics, Departments of Environmental Health Sciences & Epidemiology, Columbia University Mailman School of Public Health, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Hou+L%22">Hou L</searchLink>; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University Chicago, Evanston, IL, USA.<br /><searchLink fieldCode="AU" term="%22Conneely+K%22">Conneely K</searchLink>; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Mori+TA%22">Mori TA</searchLink>; Medical School, University of Western Australia, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Beilin+LJ%22">Beilin LJ</searchLink>; Medical School, University of Western Australia, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Huang+RC%22">Huang RC</searchLink>; Telethon Kids Institute, University of Western Australia, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Gordon-Larsen+P%22">Gordon-Larsen P</searchLink>; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, NC 27599, USA.; Carolina Population Center, University of North Carolina at Chapel Hill, NC 27516, USA.<br /><searchLink fieldCode="AU" term="%22Howard+AG%22">Howard AG</searchLink>; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Carolina Population Center, University of North Carolina at Chapel Hill, NC 27516, USA.<br /><searchLink fieldCode="AU" term="%22North+KE%22">North KE</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Carolina Population Center, University of North Carolina at Chapel Hill, NC 27516, USA.
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