Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.
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| Title: | Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score. |
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| Authors: | Knight SR; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Ho A; Medical Research Council, University of Glasgow Centre for Virus Research, Glasgow, UK.; Department of Infectious Diseases, Queen Elizabeth University Hospital, Glasgow, UK., Pius R; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Buchan I; Institute of Population Health Sciences, University of Liverpool, Liverpool, UK., Carson G; ISARIC Global Support Centre, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Drake TM; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Dunning J; National Infection Service, Public Health England, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Fairfield CJ; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Gamble C; Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK., Green CA; Institute of Microbiology & Infection, University of Birmingham, Birmingham, UK., Gupta R; Institute of Global Health, University College London, London, UK., Halpin S; Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK., Hardwick HE; NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK., Holden KA; NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK., Horby PW; ISARIC Global Support Centre, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Jackson C; Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK., Mclean KA; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Merson L; ISARIC Global Support Centre, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Nguyen-Van-Tam JS; Division of Epidemiology and Public Health, University of Nottingham School of Medicine, Nottingham, UK., Norman L; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Noursadeghi M; Division of Infection and Immunity, University College London, London, UK., Olliaro PL; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Pritchard MG; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Russell CD; Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Shaw CA; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Sheikh A; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Solomon T; NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.; Walton Centre NHS Foundation Trust, Liverpool, UK., Sudlow C; Health Data Research UK, London, UK., Swann OV; Department of Child Life and Health, University of Edinburgh, Edinburgh, UK., Turtle LC; NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.; Tropical & Infectious Disease Unit, Royal Liverpool University Hospital, Liverpool, UK., Openshaw PJ; National Heart and Lung Institute, Imperial College London, London, UK., Baillie JK; Roslin Institute, University of Edinburgh, Edinburgh, UK.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, UK., Semple MG; NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK m.g.semple@liverpool.ac.uk.; Respiratory Medicine, Alder Hey Children's Hospital, Institute in The Park, University of Liverpool, Alder Hey Children's Hospital, Liverpool L12 2AP, UK., Docherty AB; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, UK., Harrison EM; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.; Department of Clinical Surgery, University of Edinburgh, Edinburgh, UK. |
| Corporate Authors: | ISARIC4C investigators |
| Source: | BMJ (Clinical research ed.) [BMJ] 2020 Sep 09; Vol. 370, pp. m3339. Date of Electronic Publication: 2020 Sep 09. |
| Publication Type: | Journal Article; Observational Study; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: British Medical Association Country of Publication: England NLM ID: 8900488 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-1833 (Electronic) Linking ISSN: 09598138 NLM ISO Abbreviation: BMJ Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 32907855 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Knight+SR%22">Knight SR</searchLink>; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Ho+A%22">Ho A</searchLink>; Medical Research Council, University of Glasgow Centre for Virus Research, Glasgow, UK.; Department of Infectious Diseases, Queen Elizabeth University Hospital, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Pius+R%22">Pius R</searchLink>; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Buchan+I%22">Buchan I</searchLink>; Institute of Population Health Sciences, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Carson+G%22">Carson G</searchLink>; ISARIC Global Support Centre, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Drake+TM%22">Drake TM</searchLink>; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Dunning+J%22">Dunning J</searchLink>; National Infection Service, Public Health England, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Fairfield+CJ%22">Fairfield CJ</searchLink>; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Gamble+C%22">Gamble C</searchLink>; Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Green+CA%22">Green CA</searchLink>; Institute of Microbiology & Infection, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Gupta+R%22">Gupta R</searchLink>; Institute of Global Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Halpin+S%22">Halpin S</searchLink>; Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Hardwick+HE%22">Hardwick HE</searchLink>; NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Holden+KA%22">Holden KA</searchLink>; NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Horby+PW%22">Horby PW</searchLink>; ISARIC Global Support Centre, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Jackson+C%22">Jackson C</searchLink>; Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Mclean+KA%22">Mclean KA</searchLink>; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Merson+L%22">Merson L</searchLink>; ISARIC Global Support Centre, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Nguyen-Van-Tam+JS%22">Nguyen-Van-Tam JS</searchLink>; Division of Epidemiology and Public Health, University of Nottingham School of Medicine, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Norman+L%22">Norman L</searchLink>; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Noursadeghi+M%22">Noursadeghi M</searchLink>; Division of Infection and Immunity, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Olliaro+PL%22">Olliaro PL</searchLink>; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Pritchard+MG%22">Pritchard MG</searchLink>; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Russell+CD%22">Russell CD</searchLink>; Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Shaw+CA%22">Shaw CA</searchLink>; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Sheikh+A%22">Sheikh A</searchLink>; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Solomon+T%22">Solomon T</searchLink>; NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.; Walton Centre NHS Foundation Trust, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Sudlow+C%22">Sudlow C</searchLink>; Health Data Research UK, London, UK.<br /><searchLink fieldCode="AU" term="%22Swann+OV%22">Swann OV</searchLink>; Department of Child Life and Health, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Turtle+LC%22">Turtle LC</searchLink>; NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.; Tropical & Infectious Disease Unit, Royal Liverpool University Hospital, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Openshaw+PJ%22">Openshaw PJ</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Baillie+JK%22">Baillie JK</searchLink>; Roslin Institute, University of Edinburgh, Edinburgh, UK.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Semple+MG%22">Semple MG</searchLink>; NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK m.g.semple@liverpool.ac.uk.; Respiratory Medicine, Alder Hey Children's Hospital, Institute in The Park, University of Liverpool, Alder Hey Children's Hospital, Liverpool L12 2AP, UK.<br /><searchLink fieldCode="AU" term="%22Docherty+AB%22">Docherty AB</searchLink>; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Harrison+EM%22">Harrison EM</searchLink>; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.; Department of Clinical Surgery, University of Edinburgh, Edinburgh, UK. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22ISARIC4C+investigators%22">ISARIC4C investigators</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228900488%22">BMJ (Clinical research ed.)</searchLink> [BMJ] 2020 Sep 09; Vol. 370, pp. m3339. <i>Date of Electronic Publication: </i>2020 Sep 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Observational Study; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22British+Medical+Association%22">British Medical Association </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8900488 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1756-1833 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209598138%22">09598138 </searchLink><i>NLM ISO Abbreviation: </i>BMJ <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=32907855 |
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