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Structure-activity relationship studies and bioactivity evaluation of 1,2,3-triazole containing analogues as a selective sphingosine kinase-2 inhibitors.

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Title: Structure-activity relationship studies and bioactivity evaluation of 1,2,3-triazole containing analogues as a selective sphingosine kinase-2 inhibitors.
Authors: Tangadanchu VKR; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA., Jiang H; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA., Yu Y; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA., Graham TJA; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Liu H; Department of Surgery, University of Cincinnati, Cincinnati, OH, 45267, USA., Rogers BE; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA., Gropler R; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA., Perlmutter J; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA; Departments of Neurology, Neuroscience, Physical Therapy and Occupational Therapy, Washington University School of Medicine, St Louis, MO, 63110, USA., Tu Z; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA. Electronic address: tuz@mir.wustl.edu.
Source: European journal of medicinal chemistry [Eur J Med Chem] 2020 Nov 15; Vol. 206, pp. 112713. Date of Electronic Publication: 2020 Aug 08.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Tangadanchu+VKR%22">Tangadanchu VKR</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Yu+Y%22">Yu Y</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Graham+TJA%22">Graham TJA</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Department of Surgery, University of Cincinnati, Cincinnati, OH, 45267, USA.<br /><searchLink fieldCode="AU" term="%22Rogers+BE%22">Rogers BE</searchLink>; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Gropler+R%22">Gropler R</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Perlmutter+J%22">Perlmutter J</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA; Departments of Neurology, Neuroscience, Physical Therapy and Occupational Therapy, Washington University School of Medicine, St Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Tu+Z%22">Tu Z</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA. Electronic address: tuz@mir.wustl.edu.
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              Text: 2020 Nov 15
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