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S-Adenosylmethionine Rescues Cognitive Deficits in the rTg4510 Animal Model by Stabilizing Protein Phosphatase 2A and Reducing Phosphorylated Tau.

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Title: S-Adenosylmethionine Rescues Cognitive Deficits in the rTg4510 Animal Model by Stabilizing Protein Phosphatase 2A and Reducing Phosphorylated Tau.
Authors: Beauchamp LC; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Department of Pharmacology and Therapeutics, The University of Melbourne, Parkville, Australia., Liu XM; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia., Sedjahtera A; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia., Bogeski M; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia., Vella LJ; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Department of Surgery, The University of Melbourne, The Royal Melbourne Hospital, Parkville, Australia., Bush AI; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Melbourne Dementia Research Centre, The University of Melbourne, Parkville, Australia., Adlard PA; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Melbourne Dementia Research Centre, The University of Melbourne, Parkville, Australia., Barnham KJ; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Department of Pharmacology and Therapeutics, The University of Melbourne, Parkville, Australia.; Melbourne Dementia Research Centre, The University of Melbourne, Parkville, Australia.
Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2020; Vol. 77 (4), pp. 1705-1715.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE
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  Data: S-Adenosylmethionine Rescues Cognitive Deficits in the rTg4510 Animal Model by Stabilizing Protein Phosphatase 2A and Reducing Phosphorylated Tau.
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  Data: <searchLink fieldCode="AU" term="%22Beauchamp+LC%22">Beauchamp LC</searchLink>; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Department of Pharmacology and Therapeutics, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Liu+XM%22">Liu XM</searchLink>; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Sedjahtera+A%22">Sedjahtera A</searchLink>; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Bogeski+M%22">Bogeski M</searchLink>; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Vella+LJ%22">Vella LJ</searchLink>; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Department of Surgery, The University of Melbourne, The Royal Melbourne Hospital, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Bush+AI%22">Bush AI</searchLink>; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Melbourne Dementia Research Centre, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Adlard+PA%22">Adlard PA</searchLink>; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Melbourne Dementia Research Centre, The University of Melbourne, Parkville, Australia.<br /><searchLink fieldCode="AU" term="%22Barnham+KJ%22">Barnham KJ</searchLink>; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Department of Pharmacology and Therapeutics, The University of Melbourne, Parkville, Australia.; Melbourne Dementia Research Centre, The University of Melbourne, Parkville, Australia.
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  Data: <searchLink fieldCode="JN" term="%229814863%22">Journal of Alzheimer's disease : JAD</searchLink> [J Alzheimers Dis] 2020; Vol. 77 (4), pp. 1705-1715.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9814863 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1875-8908 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213872877%22">13872877 </searchLink><i>NLM ISO Abbreviation: </i>J Alzheimers Dis <i>Subsets: </i>MEDLINE
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        Value: 10.3233/JAD-200756
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      – Code: eng
        Text: English
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      – TitleFull: S-Adenosylmethionine Rescues Cognitive Deficits in the rTg4510 Animal Model by Stabilizing Protein Phosphatase 2A and Reducing Phosphorylated Tau.
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              Text: 2020
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