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Effect of CYP3A4*22 and PPAR-α Genetic Variants on Platelet Reactivity in Patients Treated with Clopidogrel and Lipid-Lowering Drugs Undergoing Elective Percutaneous Coronary Intervention.

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Title: Effect of CYP3A4*22 and PPAR-α Genetic Variants on Platelet Reactivity in Patients Treated with Clopidogrel and Lipid-Lowering Drugs Undergoing Elective Percutaneous Coronary Intervention.
Authors: Bergmeijer TO; Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands., Yasmina A; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands.; Department of Pharmacology, Faculty of Medicine, Lambung Mangkurat University, Banjarmasin 70114, Indonesia., Vos GJA; Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands., Janssen PWA; Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands., Hackeng CM; Department of Clinical Chemistry, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands., Kelder JC; Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands., Verma SS; Department of Genetics, Center for Translational Bioinformatics, Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA., Ritchie MD; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA., Gong L; Department of Biomedical Data Science and Department of Medicine, Stanford University, Stanford, CA 94305, USA., Klein TE; Department of Biomedical Data Science and Department of Medicine, Stanford University, Stanford, CA 94305, USA., Icpc Investigators, de Boer A; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands., Klungel OH; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands., Ten Berg JM; Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands., Deneer VHM; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands.; Department of Clinical Pharmacy, Division of Laboratories, Pharmacy, and Biomedical Genetics, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands.
Source: Genes [Genes (Basel)] 2020 Sep 11; Vol. 11 (9). Date of Electronic Publication: 2020 Sep 11.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of CYP3A4*22 and PPAR-α Genetic Variants on Platelet Reactivity in Patients Treated with Clopidogrel and Lipid-Lowering Drugs Undergoing Elective Percutaneous Coronary Intervention.
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  Data: <searchLink fieldCode="AU" term="%22Bergmeijer+TO%22">Bergmeijer TO</searchLink>; Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Yasmina+A%22">Yasmina A</searchLink>; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands.; Department of Pharmacology, Faculty of Medicine, Lambung Mangkurat University, Banjarmasin 70114, Indonesia.<br /><searchLink fieldCode="AU" term="%22Vos+GJA%22">Vos GJA</searchLink>; Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Janssen+PWA%22">Janssen PWA</searchLink>; Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hackeng+CM%22">Hackeng CM</searchLink>; Department of Clinical Chemistry, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kelder+JC%22">Kelder JC</searchLink>; Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Verma+SS%22">Verma SS</searchLink>; Department of Genetics, Center for Translational Bioinformatics, Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Ritchie+MD%22">Ritchie MD</searchLink>; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Gong+L%22">Gong L</searchLink>; Department of Biomedical Data Science and Department of Medicine, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Klein+TE%22">Klein TE</searchLink>; Department of Biomedical Data Science and Department of Medicine, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Icpc+Investigators%22">Icpc Investigators</searchLink><br /><searchLink fieldCode="AU" term="%22de+Boer+A%22">de Boer A</searchLink>; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Klungel+OH%22">Klungel OH</searchLink>; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ten+Berg+JM%22">Ten Berg JM</searchLink>; Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Deneer+VHM%22">Deneer VHM</searchLink>; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands.; Department of Clinical Pharmacy, Division of Laboratories, Pharmacy, and Biomedical Genetics, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands.
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