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B cell acute lymphoblastic leukemia cells mediate RANK-RANKL-dependent bone destruction.

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Title: B cell acute lymphoblastic leukemia cells mediate RANK-RANKL-dependent bone destruction.
Authors: Rajakumar SA; Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Papp E; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada., Lee KK; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3H7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Grandal I; Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada., Merico D; Center for Applied Genomics, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada., Liu CC; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3H7, Canada.; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Allo B; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3H7, Canada., Zhang L; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3H7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Grynpas MD; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3H7, Canada.; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Minden MD; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 2M9, Canada., Hitzler JK; Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.; Department of Pediatrics, Division of Hematology and Oncology, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada., Guidos CJ; Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Danska JS; Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada. jayne.danska@sickkids.ca.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Source: Science translational medicine [Sci Transl Med] 2020 Sep 16; Vol. 12 (561).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: B cell acute lymphoblastic leukemia cells mediate RANK-RANKL-dependent bone destruction.
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  Data: <searchLink fieldCode="AU" term="%22Rajakumar+SA%22">Rajakumar SA</searchLink>; Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Papp+E%22">Papp E</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Lee+KK%22">Lee KK</searchLink>; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3H7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Grandal+I%22">Grandal I</searchLink>; Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Merico+D%22">Merico D</searchLink>; Center for Applied Genomics, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.<br /><searchLink fieldCode="AU" term="%22Liu+CC%22">Liu CC</searchLink>; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3H7, Canada.; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Allo+B%22">Allo B</searchLink>; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3H7, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3H7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Grynpas+MD%22">Grynpas MD</searchLink>; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3H7, Canada.; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Minden+MD%22">Minden MD</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 2M9, Canada.<br /><searchLink fieldCode="AU" term="%22Hitzler+JK%22">Hitzler JK</searchLink>; Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.; Department of Pediatrics, Division of Hematology and Oncology, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.<br /><searchLink fieldCode="AU" term="%22Guidos+CJ%22">Guidos CJ</searchLink>; Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Danska+JS%22">Danska JS</searchLink>; Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada. jayne.danska@sickkids.ca.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
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