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IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration.

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Title: IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration.
Authors: Dagher R; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France.; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France.; Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Copenhaver AM; Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Besnard V; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France.; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France., Berlin A; Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Hamidi F; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France.; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France., Maret M; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France.; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France., Wang J; Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Qu X; Data Sciences and AI, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Shrestha Y; Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, MD, USA., Wu J; Data Sciences and AI, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Gautier G; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France.; Inserm UMR1149 - Centre de Recherche sur l'Inflammation, Université Paris, Paris, France., Raja R; Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, MD, USA., Aubier M; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France.; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France., Kolbeck R; Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Humbles AA; Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA. alisonhumbles@gmail.com., Pretolani M; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France. marina.pretolani@inserm.fr.; Faculté de Médecine, Université Paris, Paris, France. marina.pretolani@inserm.fr.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France. marina.pretolani@inserm.fr.
Source: Nature communications [Nat Commun] 2020 Sep 22; Vol. 11 (1), pp. 4786. Date of Electronic Publication: 2020 Sep 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration.
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  Data: <searchLink fieldCode="AU" term="%22Dagher+R%22">Dagher R</searchLink>; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France.; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France.; Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Copenhaver+AM%22">Copenhaver AM</searchLink>; Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Besnard+V%22">Besnard V</searchLink>; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France.; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France.<br /><searchLink fieldCode="AU" term="%22Berlin+A%22">Berlin A</searchLink>; Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hamidi+F%22">Hamidi F</searchLink>; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France.; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France.<br /><searchLink fieldCode="AU" term="%22Maret+M%22">Maret M</searchLink>; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France.; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Qu+X%22">Qu X</searchLink>; Data Sciences and AI, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Shrestha+Y%22">Shrestha Y</searchLink>; Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; Data Sciences and AI, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gautier+G%22">Gautier G</searchLink>; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France.; Inserm UMR1149 - Centre de Recherche sur l'Inflammation, Université Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Raja+R%22">Raja R</searchLink>; Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Aubier+M%22">Aubier M</searchLink>; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France.; Faculté de Médecine, Université Paris, Paris, France.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France.<br /><searchLink fieldCode="AU" term="%22Kolbeck+R%22">Kolbeck R</searchLink>; Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Humbles+AA%22">Humbles AA</searchLink>; Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA. alisonhumbles@gmail.com.<br /><searchLink fieldCode="AU" term="%22Pretolani+M%22">Pretolani M</searchLink>; Inserm UMR1152-Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris, Paris, France. marina.pretolani@inserm.fr.; Faculté de Médecine, Université Paris, Paris, France. marina.pretolani@inserm.fr.; Laboratoire d'Excellence (LabEx) INFLAMEX and Département Hospitalo-Universitaire (DHU) FIRE, Paris, France. marina.pretolani@inserm.fr.
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