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Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.

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Title: Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
Authors: Yurkovetskiy L; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA., Wang X; Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG Eindhoven, Netherlands., Pascal KE; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591, USA., Tomkins-Tinch C; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA; Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA., Nyalile TP; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA., Wang Y; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA., Baum A; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591, USA., Diehl WE; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA., Dauphin A; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA., Carbone C; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA., Veinotte K; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA., Egri SB; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA., Schaffner SF; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA; Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA., Lemieux JE; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA; Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA., Munro JB; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01605, USA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation St, Worcester, MA 01605, USA., Rafique A; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591, USA., Barve A; Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG Eindhoven, Netherlands., Sabeti PC; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA; Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA; Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, 02115 Boston, MA, USA; Howard Hughes Medical Institute, 4000 Jones Bridge Rd, Chevy Chase, MD 20815, USA; Massachusetts Consortium on Pathogen Readiness, Boston, MA, 02115, USA. Electronic address: pardis.sabeti@broadinstitute.org., Kyratsous CA; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591, USA. Electronic address: christos.kyratsous@regeneron.com., Dudkina NV; Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG Eindhoven, Netherlands. Electronic address: natalya.dudkina@thermofisher.com., Shen K; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA. Electronic address: kuang.shen@umassmed.edu., Luban J; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation St, Worcester, MA 01605, USA; Massachusetts Consortium on Pathogen Readiness, Boston, MA, 02115, USA. Electronic address: jeremy.luban@umassmed.edu.
Source: Cell [Cell] 2020 Oct 29; Vol. 183 (3), pp. 739-751.e8. Date of Electronic Publication: 2020 Sep 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
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  Data: Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
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  Data: <searchLink fieldCode="AU" term="%22Yurkovetskiy+L%22">Yurkovetskiy L</searchLink>; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Pascal+KE%22">Pascal KE</searchLink>; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591, USA.<br /><searchLink fieldCode="AU" term="%22Tomkins-Tinch+C%22">Tomkins-Tinch C</searchLink>; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA; Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA.<br /><searchLink fieldCode="AU" term="%22Nyalile+TP%22">Nyalile TP</searchLink>; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Baum+A%22">Baum A</searchLink>; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591, USA.<br /><searchLink fieldCode="AU" term="%22Diehl+WE%22">Diehl WE</searchLink>; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Dauphin+A%22">Dauphin A</searchLink>; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Carbone+C%22">Carbone C</searchLink>; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Veinotte+K%22">Veinotte K</searchLink>; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Egri+SB%22">Egri SB</searchLink>; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Schaffner+SF%22">Schaffner SF</searchLink>; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA; Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA.<br /><searchLink fieldCode="AU" term="%22Lemieux+JE%22">Lemieux JE</searchLink>; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA; Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.<br /><searchLink fieldCode="AU" term="%22Munro+JB%22">Munro JB</searchLink>; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01605, USA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation St, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Rafique+A%22">Rafique A</searchLink>; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591, USA.<br /><searchLink fieldCode="AU" term="%22Barve+A%22">Barve A</searchLink>; Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sabeti+PC%22">Sabeti PC</searchLink>; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA; Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA; Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, 02115 Boston, MA, USA; Howard Hughes Medical Institute, 4000 Jones Bridge Rd, Chevy Chase, MD 20815, USA; Massachusetts Consortium on Pathogen Readiness, Boston, MA, 02115, USA. Electronic address: pardis.sabeti@broadinstitute.org.<br /><searchLink fieldCode="AU" term="%22Kyratsous+CA%22">Kyratsous CA</searchLink>; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591, USA. Electronic address: christos.kyratsous@regeneron.com.<br /><searchLink fieldCode="AU" term="%22Dudkina+NV%22">Dudkina NV</searchLink>; Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG Eindhoven, Netherlands. Electronic address: natalya.dudkina@thermofisher.com.<br /><searchLink fieldCode="AU" term="%22Shen+K%22">Shen K</searchLink>; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA. Electronic address: kuang.shen@umassmed.edu.<br /><searchLink fieldCode="AU" term="%22Luban+J%22">Luban J</searchLink>; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation St, Worcester, MA 01605, USA; Massachusetts Consortium on Pathogen Readiness, Boston, MA, 02115, USA. Electronic address: jeremy.luban@umassmed.edu.
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  Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2020 Oct 29; Vol. 183 (3), pp. 739-751.e8. <i>Date of Electronic Publication: </i>2020 Sep 15.
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