A Stearoyl-Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α-Synuclein Mice.

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Title: A Stearoyl-Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α-Synuclein Mice.
Authors: Nuber S; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Nam AY; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Rajsombath MM; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Cirka H; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Hronowski X; Chemical Biology & Proteomics, Biogen, Cambridge, MA, USA., Wang J; Chemical Biology & Proteomics, Biogen, Cambridge, MA, USA., Hodgetts K; Laboratory for Drug Discovery in Neurodegeneration, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Kalinichenko LS; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany., Müller CP; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany., Lambrecht V; Division of Molecular Neurology, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany., Winkler J; Division of Molecular Neurology, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany., Weihofen A; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA., Imberdis T; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Dettmer U; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Fanning S; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Selkoe DJ; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Source: Annals of neurology [Ann Neurol] 2021 Jan; Vol. 89 (1), pp. 74-90. Date of Electronic Publication: 2020 Oct 23.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7707449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8249 (Electronic) Linking ISSN: 03645134 NLM ISO Abbreviation: Ann Neurol Subsets: MEDLINE
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  Data: A Stearoyl-Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α-Synuclein Mice.
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  Data: <searchLink fieldCode="AU" term="%22Nuber+S%22">Nuber S</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nam+AY%22">Nam AY</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rajsombath+MM%22">Rajsombath MM</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cirka+H%22">Cirka H</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hronowski+X%22">Hronowski X</searchLink>; Chemical Biology & Proteomics, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Chemical Biology & Proteomics, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hodgetts+K%22">Hodgetts K</searchLink>; Laboratory for Drug Discovery in Neurodegeneration, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kalinichenko+LS%22">Kalinichenko LS</searchLink>; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+CP%22">Müller CP</searchLink>; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Lambrecht+V%22">Lambrecht V</searchLink>; Division of Molecular Neurology, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Winkler+J%22">Winkler J</searchLink>; Division of Molecular Neurology, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Weihofen+A%22">Weihofen A</searchLink>; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Imberdis+T%22">Imberdis T</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dettmer+U%22">Dettmer U</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fanning+S%22">Fanning S</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Selkoe+DJ%22">Selkoe DJ</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%227707449%22">Annals of neurology</searchLink> [Ann Neurol] 2021 Jan; Vol. 89 (1), pp. 74-90. <i>Date of Electronic Publication: </i>2020 Oct 23.
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