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TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control.

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Title: TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control.
Authors: Douse CH; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.; Department of Experimental Medical Science, Lund University, Lund, Sweden., Tchasovnikarova IA; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.; The Gurdon Institute, Cambridge, UK., Timms RT; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK., Protasio AV; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Seczynska M; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK., Prigozhin DM; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Albecka A; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.; MRC Laboratory of Molecular Biology, Cambridge, UK., Wagstaff J; Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK., Williamson JC; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK., Freund SMV; Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK., Lehner PJ; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK. pjl30@cam.ac.uk., Modis Y; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK. ymodis@mrc-lmb.cam.ac.uk.; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK. ymodis@mrc-lmb.cam.ac.uk.
Source: Nature communications [Nat Commun] 2020 Oct 02; Vol. 11 (1), pp. 4940. Date of Electronic Publication: 2020 Oct 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control.
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  Data: <searchLink fieldCode="AU" term="%22Douse+CH%22">Douse CH</searchLink>; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.; Department of Experimental Medical Science, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Tchasovnikarova+IA%22">Tchasovnikarova IA</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.; The Gurdon Institute, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Timms+RT%22">Timms RT</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.<br /><searchLink fieldCode="AU" term="%22Protasio+AV%22">Protasio AV</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.; Department of Pathology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Seczynska+M%22">Seczynska M</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.<br /><searchLink fieldCode="AU" term="%22Prigozhin+DM%22">Prigozhin DM</searchLink>; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Albecka+A%22">Albecka A</searchLink>; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.; MRC Laboratory of Molecular Biology, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Wagstaff+J%22">Wagstaff J</searchLink>; Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.<br /><searchLink fieldCode="AU" term="%22Williamson+JC%22">Williamson JC</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.<br /><searchLink fieldCode="AU" term="%22Freund+SMV%22">Freund SMV</searchLink>; Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.<br /><searchLink fieldCode="AU" term="%22Lehner+PJ%22">Lehner PJ</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK. pjl30@cam.ac.uk.<br /><searchLink fieldCode="AU" term="%22Modis+Y%22">Modis Y</searchLink>; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK. ymodis@mrc-lmb.cam.ac.uk.; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK. ymodis@mrc-lmb.cam.ac.uk.
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