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Intratumoral nanoplexed poly I:C BO-112 in combination with systemic anti-PD-1 for patients with anti-PD-1-refractory tumors.

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Title: Intratumoral nanoplexed poly I:C BO-112 in combination with systemic anti-PD-1 for patients with anti-PD-1-refractory tumors.
Authors: Márquez-Rodas I; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain. ivanpantic@hotmail.com., Longo F; Medical Oncology Department, Hospital Ramón y Cajal, IRYCIS and CIBERONC, Madrid28034, Spain., Rodriguez-Ruiz ME; CIMA and Clínica Universidad de Navarra and CIBERONC, Pamplona 31008, Spain., Calles A; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain., Ponce S; Medical Oncology Department, Hospital 12 de Octubre, Madrid 28041, Spain., Jove M; Medical Oncology Department, Institut Català d'Oncologia, Barcelona 08908, Spain., Rubio-Viqueira B; Medical Oncology Department, Hospital Universitario Quirónsalud, Madrid 28223, Spain., Perez-Gracia JL; Medical Oncology Department, Clínica Universidad de Navarra, Pamplona 31008, Spain., Gómez-Rueda A; Medical Oncology Department, Hospital Ramón y Cajal, IRYCIS and CIBERONC, Madrid28034, Spain., López-Tarruella S; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain., Ponz-Sarvise M; CIMA and Clínica Universidad de Navarra and CIBERONC, Pamplona 31008, Spain., Álvarez R; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain., Soria-Rivas A; Medical Oncology Department, Hospital Ramón y Cajal, IRYCIS and CIBERONC, Madrid28034, Spain., de Miguel E; Radiology Department, Hospital General Universitario Gregorio Marañón, Madrid 28007, Spain., Ramos-Medina R; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain., Castañon E; Medical Oncology Department, Clínica Universidad de Navarra, Pamplona 31008, Spain., Gajate P; Medical Oncology Department, Hospital Ramón y Cajal, IRYCIS and CIBERONC, Madrid28034, Spain., Sempere-Ortega C; Radiology Department, Hospital Ramón y Cajal, Madrid 28034, Spain., Jiménez-Aguilar E; Medical Oncology Department, Hospital 12 de Octubre, Madrid 28041, Spain., Aznar MA; CIMA and Clínica Universidad de Navarra and CIBERONC, Pamplona 31008, Spain., Calvo A; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain., Lopez-Casas PP; Highlight Therapeutics (formerly known as Bioncotech Therapeutics), Valencia 46980, Spain., Martín-Algarra S; Medical Oncology Department, Clínica Universidad de Navarra, Pamplona 31008, Spain., Martín M; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain., Tersago D; Highlight Therapeutics (formerly known as Bioncotech Therapeutics), Valencia 46980, Spain., Quintero M; CIMA and Clínica Universidad de Navarra and CIBERONC, Pamplona 31008, Spain., Melero I; CIMA and Clínica Universidad de Navarra and CIBERONC, Pamplona 31008, Spain.
Source: Science translational medicine [Sci Transl Med] 2020 Oct 14; Vol. 12 (565).
Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intratumoral nanoplexed poly I:C BO-112 in combination with systemic anti-PD-1 for patients with anti-PD-1-refractory tumors.
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  Data: <searchLink fieldCode="AU" term="%22Márquez-Rodas+I%22">Márquez-Rodas I</searchLink>; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain. ivanpantic@hotmail.com.<br /><searchLink fieldCode="AU" term="%22Longo+F%22">Longo F</searchLink>; Medical Oncology Department, Hospital Ramón y Cajal, IRYCIS and CIBERONC, Madrid28034, Spain.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Ruiz+ME%22">Rodriguez-Ruiz ME</searchLink>; CIMA and Clínica Universidad de Navarra and CIBERONC, Pamplona 31008, Spain.<br /><searchLink fieldCode="AU" term="%22Calles+A%22">Calles A</searchLink>; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain.<br /><searchLink fieldCode="AU" term="%22Ponce+S%22">Ponce S</searchLink>; Medical Oncology Department, Hospital 12 de Octubre, Madrid 28041, Spain.<br /><searchLink fieldCode="AU" term="%22Jove+M%22">Jove M</searchLink>; Medical Oncology Department, Institut Català d'Oncologia, Barcelona 08908, Spain.<br /><searchLink fieldCode="AU" term="%22Rubio-Viqueira+B%22">Rubio-Viqueira B</searchLink>; Medical Oncology Department, Hospital Universitario Quirónsalud, Madrid 28223, Spain.<br /><searchLink fieldCode="AU" term="%22Perez-Gracia+JL%22">Perez-Gracia JL</searchLink>; Medical Oncology Department, Clínica Universidad de Navarra, Pamplona 31008, Spain.<br /><searchLink fieldCode="AU" term="%22Gómez-Rueda+A%22">Gómez-Rueda A</searchLink>; Medical Oncology Department, Hospital Ramón y Cajal, IRYCIS and CIBERONC, Madrid28034, Spain.<br /><searchLink fieldCode="AU" term="%22López-Tarruella+S%22">López-Tarruella S</searchLink>; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain.<br /><searchLink fieldCode="AU" term="%22Ponz-Sarvise+M%22">Ponz-Sarvise M</searchLink>; CIMA and Clínica Universidad de Navarra and CIBERONC, Pamplona 31008, Spain.<br /><searchLink fieldCode="AU" term="%22Álvarez+R%22">Álvarez R</searchLink>; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain.<br /><searchLink fieldCode="AU" term="%22Soria-Rivas+A%22">Soria-Rivas A</searchLink>; Medical Oncology Department, Hospital Ramón y Cajal, IRYCIS and CIBERONC, Madrid28034, Spain.<br /><searchLink fieldCode="AU" term="%22de+Miguel+E%22">de Miguel E</searchLink>; Radiology Department, Hospital General Universitario Gregorio Marañón, Madrid 28007, Spain.<br /><searchLink fieldCode="AU" term="%22Ramos-Medina+R%22">Ramos-Medina R</searchLink>; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain.<br /><searchLink fieldCode="AU" term="%22Castañon+E%22">Castañon E</searchLink>; Medical Oncology Department, Clínica Universidad de Navarra, Pamplona 31008, Spain.<br /><searchLink fieldCode="AU" term="%22Gajate+P%22">Gajate P</searchLink>; Medical Oncology Department, Hospital Ramón y Cajal, IRYCIS and CIBERONC, Madrid28034, Spain.<br /><searchLink fieldCode="AU" term="%22Sempere-Ortega+C%22">Sempere-Ortega C</searchLink>; Radiology Department, Hospital Ramón y Cajal, Madrid 28034, Spain.<br /><searchLink fieldCode="AU" term="%22Jiménez-Aguilar+E%22">Jiménez-Aguilar E</searchLink>; Medical Oncology Department, Hospital 12 de Octubre, Madrid 28041, Spain.<br /><searchLink fieldCode="AU" term="%22Aznar+MA%22">Aznar MA</searchLink>; CIMA and Clínica Universidad de Navarra and CIBERONC, Pamplona 31008, Spain.<br /><searchLink fieldCode="AU" term="%22Calvo+A%22">Calvo A</searchLink>; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain.<br /><searchLink fieldCode="AU" term="%22Lopez-Casas+PP%22">Lopez-Casas PP</searchLink>; Highlight Therapeutics (formerly known as Bioncotech Therapeutics), Valencia 46980, Spain.<br /><searchLink fieldCode="AU" term="%22Martín-Algarra+S%22">Martín-Algarra S</searchLink>; Medical Oncology Department, Clínica Universidad de Navarra, Pamplona 31008, Spain.<br /><searchLink fieldCode="AU" term="%22Martín+M%22">Martín M</searchLink>; Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERONC, Madrid 28007, Spain.<br /><searchLink fieldCode="AU" term="%22Tersago+D%22">Tersago D</searchLink>; Highlight Therapeutics (formerly known as Bioncotech Therapeutics), Valencia 46980, Spain.<br /><searchLink fieldCode="AU" term="%22Quintero+M%22">Quintero M</searchLink>; CIMA and Clínica Universidad de Navarra and CIBERONC, Pamplona 31008, Spain.<br /><searchLink fieldCode="AU" term="%22Melero+I%22">Melero I</searchLink>; CIMA and Clínica Universidad de Navarra and CIBERONC, Pamplona 31008, Spain.
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