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Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings.

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Title: Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings.
Authors: Gupta RK; Institute for Global Health, University College London, London, UK., Calderwood CJ; Institute for Global Health, University College London, London, UK., Yavlinsky A; Institute of Health Informatics, University College London, London, UK., Krutikov M; Institute for Global Health, University College London, London, UK., Quartagno M; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK., Aichelburg MC; Department of Dermatology, Sozialmedizinisches Zentrum Ost-Donauspital, Vienna, Austria., Altet N; Unitat de Tuberculosis, Hospital Universitari Vall d'Hebron-Drassanes, Barcelona, Spain.; Unitat de TDO de la Tuberculosis 'Servicios Clínicos', Barcelona, Spain., Diel R; Institute for Epidemiology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.; Lung Clinic Grosshansdorf, Airway Research Center North (ARCN), Großhansdorf, Germany., Dobler CC; Institute for Evidence-Based Healthcare, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Queensland, Australia.; Department of Respiratory Medicine, Liverpool Hospital, Sydney, Australia., Dominguez J; Institut d'Investigació Germans Trias i Pujol, Badalona, Barcelona, Spain.; CIBER Enfermedades Respiratorias, Badalona, Barcelona, Spain.; Universitat Autònoma de Barcelona, Badalona, Barcelona, Spain., Doyle JS; Department of Infectious Diseases, The Alfred and Monash University, Melbourne, Australia.; Disease Elimination Program, Burnet Institute, Melbourne, Australia., Erkens C; KNCV Tuberculosis Foundation, The Hague, The Netherlands., Geis S; Institute for Medical Microbiology and Hospital Hygiene, Philipps University of Marburg, Marburg, Germany., Haldar P; Respiratory Biomedical Research Centre, Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Hauri AM; Hesse State Health Office, Dillenburg, Germany., Hermansen T; International Reference Laboratory of Mycobacteriology, Statens Serum Institut, Copenhagen, Denmark., Johnston JC; British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada., Lange C; Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.; German Center for Infection Research (DZIF), Clinical Tuberculosis Center, Borstel, Germany.; Tuberculosis Network European Trials Group (TBnet), Borstel, Germany.; Department of Medicine, Karolinska Institute, Stockholm, Sweden., Lange B; Department of Epidemiology, Helmholtz Centre for Infection Research, Braunschweig, Germany., van Leth F; Tuberculosis Network European Trials Group (TBnet), Borstel, Germany.; Amsterdam Institute for Global Health and Development, Amsterdam, the Netherlands.; Department of Global Health, Amsterdam University Medical Centres, Amsterdam, the Netherlands., Muñoz L; Department of Clinical Sciences, University of Barcelona, Barcelona, Spain., Roder C; Department of Infectious Diseases, The Alfred and Monash University, Melbourne, Australia.; Disease Elimination Program, Burnet Institute, Melbourne, Australia., Romanowski K; British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada., Roth D; British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada., Sester M; Tuberculosis Network European Trials Group (TBnet), Borstel, Germany.; Department of Transplant and Infection Immunology, Saarland University, Homburg, Germany., Sloot R; Department of Paediatrics and Child Health, Desmond Tutu TB Centre, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Sotgiu G; Tuberculosis Network European Trials Group (TBnet), Borstel, Germany.; Clinical Epidemiology and Medical Statistics Unit, Department of Medical, Surgical and Experimental Sciences, Uniiversity of Sassari, Sassari, Italy., Woltmann G; Respiratory Biomedical Research Centre, Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Yoshiyama T; Research Institute of Tuberculosis, Tokyo, Japan., Zellweger JP; Tuberculosis Network European Trials Group (TBnet), Borstel, Germany.; Swiss Lung Association, Berne, Switzerland., Zenner D; Institute for Global Health, University College London, London, UK., Aldridge RW; Institute of Health Informatics, University College London, London, UK., Copas A; Institute for Global Health, University College London, London, UK.; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK., Rangaka MX; Institute for Global Health, University College London, London, UK.; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK.; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.; Division of Epidemiology and Biostatistics, School of Public Health, University of Cape Town, Cape Town, South Africa., Lipman M; UCL-TB and UCL Respiratory, University College London, London, UK.; Royal Free London NHS Foundation Trust, London, UK., Noursadeghi M; Division of Infection & Immunity, University College London, London, UK., Abubakar I; Institute for Global Health, University College London, London, UK. i.abubakar@ucl.ac.uk.
Source: Nature medicine [Nat Med] 2020 Dec; Vol. 26 (12), pp. 1941-1949. Date of Electronic Publication: 2020 Oct 19.
Publication Type: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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