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Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity.

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Title: Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity.
Authors: Punt S; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Malu S; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; Immunitas Therapeutics, Cambridge, MA, USA., McKenzie JA; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; Eisai Inc., Woodcliff Lake, NJ, USA., Manrique SZ; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Doorduijn EM; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Mbofung RM; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; Merck Research Laboratories, Palo Alto, CA, USA., Williams L; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; KSQ Therapeutics Inc., Cambridge, MA, USA., Silverman DA; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Ashkin EL; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Dominguez AL; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Wang Z; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; Nature Cell Biology, Springer Nature, Shanghai City, China., Chen JQ; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; EMD Serono, Rockland, MA, USA., Maiti SN; Department of Pediatrics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Tieu TN; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; C4 Therapeutics, Watertown, MA, USA., Liu C; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Xu C; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; University of Houston, Houston, TX, USA., Forget MA; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Haymaker C; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Khalili JS; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; SystImmune Inc., Redmond, WA, USA., Satani N; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Muller F; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Cooper LJN; Department of Pediatrics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; ZIOPHARM Oncology Inc., Boston, MA, USA., Overwijk WW; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; Nektar Therapeutics, San Francisco, CA, USA., Amaria RN; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Bernatchez C; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Heffernan TP; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Peng W; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; University of Houston, Houston, TX, USA., Roszik J; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Hwu P; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA. phwu@mdanderson.org.; Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA. phwu@mdanderson.org.; Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. phwu@mdanderson.org.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Apr; Vol. 70 (4), pp. 1101-1113. Date of Electronic Publication: 2020 Oct 29.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
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  Data: Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity.
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  Data: <searchLink fieldCode="AU" term="%22Punt+S%22">Punt S</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Malu+S%22">Malu S</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; Immunitas Therapeutics, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22McKenzie+JA%22">McKenzie JA</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; Eisai Inc., Woodcliff Lake, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Manrique+SZ%22">Manrique SZ</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Doorduijn+EM%22">Doorduijn EM</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Mbofung+RM%22">Mbofung RM</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; Merck Research Laboratories, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Williams+L%22">Williams L</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; KSQ Therapeutics Inc., Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Silverman+DA%22">Silverman DA</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Ashkin+EL%22">Ashkin EL</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Dominguez+AL%22">Dominguez AL</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; Nature Cell Biology, Springer Nature, Shanghai City, China.<br /><searchLink fieldCode="AU" term="%22Chen+JQ%22">Chen JQ</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; EMD Serono, Rockland, MA, USA.<br /><searchLink fieldCode="AU" term="%22Maiti+SN%22">Maiti SN</searchLink>; Department of Pediatrics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Tieu+TN%22">Tieu TN</searchLink>; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; C4 Therapeutics, Watertown, MA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; University of Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Forget+MA%22">Forget MA</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Haymaker+C%22">Haymaker C</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Khalili+JS%22">Khalili JS</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; SystImmune Inc., Redmond, WA, USA.<br /><searchLink fieldCode="AU" term="%22Satani+N%22">Satani N</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Muller+F%22">Muller F</searchLink>; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Cooper+LJN%22">Cooper LJN</searchLink>; Department of Pediatrics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; ZIOPHARM Oncology Inc., Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Overwijk+WW%22">Overwijk WW</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; Nektar Therapeutics, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Amaria+RN%22">Amaria RN</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Bernatchez+C%22">Bernatchez C</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Heffernan+TP%22">Heffernan TP</searchLink>; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Peng+W%22">Peng W</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.; University of Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Roszik+J%22">Roszik J</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Hwu+P%22">Hwu P</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA. phwu@mdanderson.org.; Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA. phwu@mdanderson.org.; Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. phwu@mdanderson.org.
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