Antibody binding to native cytomegalovirus glycoprotein B predicts efficacy of the gB/MF59 vaccine in humans.

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Title: Antibody binding to native cytomegalovirus glycoprotein B predicts efficacy of the gB/MF59 vaccine in humans.
Authors: Jenks JA; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27705, USA., Nelson CS; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27705, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Roark HK; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27705, USA., Goodwin ML; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27705, USA., Pass RF; Department of Pediatrics, University of Alabama of Birmingham, Birmingham, AL 35233, USA., Bernstein DI; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA., Walter EB; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27705, USA., Edwards KM; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Wang D; Merck & Co. Inc., Kenilworth, NJ 07033, USA., Fu TM; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX 77030, USA., An Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX 77030, USA., Chan C; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC 27705, USA., Permar SR; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27705, USA. sallie.permar@duke.edu.; Department of Pediatrics, Duke University Medical Center, Durham, NC 27705, USA.
Source: Science translational medicine [Sci Transl Med] 2020 Nov 04; Vol. 12 (568).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.abb3611