Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis.
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| Title: | Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis. |
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| Authors: | Moreira-Teixeira L; Laboratory of Immunoregulation and Infection, The Francis Crick Institute, London, NW1 1AT, UK. luciamoreirateixeira@gmail.com., Stimpson PJ; Laboratory of Immunoregulation and Infection, The Francis Crick Institute, London, NW1 1AT, UK., Stavropoulos E; Laboratory of Immunoregulation and Infection, The Francis Crick Institute, London, NW1 1AT, UK., Hadebe S; Laboratory of Immunoregulation and Infection, The Francis Crick Institute, London, NW1 1AT, UK., Chakravarty P; Bioinformatics and Biostatistics Team, The Francis Crick Institute, London, NW1 1AT, UK., Ioannou M; Laboratory of Antimicrobial Defence, The Francis Crick Institute, London, NW1 1AT, UK., Aramburu IV; Laboratory of Antimicrobial Defence, The Francis Crick Institute, London, NW1 1AT, UK., Herbert E; Department of Pathobiology and Population Sciences, Royal Veterinary College, Hatfield, AL9 7TA, UK.; Experimental Histopathology Team, The Francis Crick Institute, London, NW1 1AT, UK., Priestnall SL; Department of Pathobiology and Population Sciences, Royal Veterinary College, Hatfield, AL9 7TA, UK.; Experimental Histopathology Team, The Francis Crick Institute, London, NW1 1AT, UK., Suarez-Bonnet A; Department of Pathobiology and Population Sciences, Royal Veterinary College, Hatfield, AL9 7TA, UK.; Experimental Histopathology Team, The Francis Crick Institute, London, NW1 1AT, UK., Sousa J; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.; IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal.; ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal., Fonseca KL; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.; IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal.; ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.; Programa de Pós-Graduação Ciência para o Desenvolvimento (PGCD), Instituto Gulbenkian de Ciência (IGC), Oeiras, Portugal., Wang Q; Laboratory of Antimicrobial Defence, The Francis Crick Institute, London, NW1 1AT, UK., Vashakidze S; National Center for Tuberculosis and Lung Diseases (NCTLD), 50, Maruashvili Str, 0101, Tbilisi, Georgia., Rodríguez-Martínez P; Pathology Department, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), Crtra. Del Canyet, s/n, 08916, Badalona, Catalonia, Spain., Vilaplana C; Experimental Tuberculosis Unit (UTE), Fundació Institut Germans Trias i Pujol (IGTP), Universitat Autònoma de Barcelona (UAB), CIBER Enfermedades Respiratorias. Edifici Laboratoris de Recerca. Can Ruti Campus, Crtra. de Can Ruti, Camí de les Escoles, s/n, 08916, Badalona, Catalonia, Spain., Saraiva M; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.; IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal., Papayannopoulos V; Laboratory of Antimicrobial Defence, The Francis Crick Institute, London, NW1 1AT, UK., O'Garra A; Laboratory of Immunoregulation and Infection, The Francis Crick Institute, London, NW1 1AT, UK.; National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, W2 1PG, UK. |
| Source: | Nature communications [Nat Commun] 2020 Nov 04; Vol. 11 (1), pp. 5566. Date of Electronic Publication: 2020 Nov 04. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-020-19412-6 |
