Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors.
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| Title: | Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors. |
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| Authors: | Mohamed MFA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, 82524 Sohag, Egypt. Electronic address: mamdouh.fawzi@pharm.sohag.edu.eg., Marzouk AA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, 71524 Assiut, Egypt., Nafady A; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia., El-Gamal DA; Histology Department, Faculty of Medicine, Assiut University, 71526 Assiut, Egypt., Allam RM; Pharmacology Department, National Research Centre, Giza 11865, Egypt., Abuo-Rahma GEA; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt., El Subbagh HI; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, 35516 Mansoura, Egypt., Moustafa AH; Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt. |
| Source: | Bioorganic chemistry [Bioorg Chem] 2020 Dec; Vol. 105, pp. 104439. Date of Electronic Publication: 2020 Oct 28. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 33161252 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Mohamed+MFA%22">Mohamed MFA</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, 82524 Sohag, Egypt. Electronic address: mamdouh.fawzi@pharm.sohag.edu.eg.<br /><searchLink fieldCode="AU" term="%22Marzouk+AA%22">Marzouk AA</searchLink>; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, 71524 Assiut, Egypt.<br /><searchLink fieldCode="AU" term="%22Nafady+A%22">Nafady A</searchLink>; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22El-Gamal+DA%22">El-Gamal DA</searchLink>; Histology Department, Faculty of Medicine, Assiut University, 71526 Assiut, Egypt.<br /><searchLink fieldCode="AU" term="%22Allam+RM%22">Allam RM</searchLink>; Pharmacology Department, National Research Centre, Giza 11865, Egypt.<br /><searchLink fieldCode="AU" term="%22Abuo-Rahma+GEA%22">Abuo-Rahma GEA</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.<br /><searchLink fieldCode="AU" term="%22El+Subbagh+HI%22">El Subbagh HI</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, 35516 Mansoura, Egypt.<br /><searchLink fieldCode="AU" term="%22Moustafa+AH%22">Moustafa AH</searchLink>; Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2020 Dec; Vol. 105, pp. 104439. <i>Date of Electronic Publication: </i>2020 Oct 28. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1303703 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2120 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200452068%22">00452068 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=33161252 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.bioorg.2020.104439 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 104439 Titles: – TitleFull: Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Mohamed MFA – PersonEntity: Name: NameFull: Marzouk AA – PersonEntity: Name: NameFull: Nafady A – PersonEntity: Name: NameFull: El-Gamal DA – PersonEntity: Name: NameFull: Allam RM – PersonEntity: Name: NameFull: Abuo-Rahma GEA – PersonEntity: Name: NameFull: El Subbagh HI – PersonEntity: Name: NameFull: Moustafa AH IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2020 Dec Type: published Y: 2020 Identifiers: – Type: issn-electronic Value: 1090-2120 Numbering: – Type: volume Value: 105 Titles: – TitleFull: Bioorganic chemistry Type: main |
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