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CD28 Costimulatory Domain-Targeted Mutations Enhance Chimeric Antigen Receptor T-cell Function.

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Title: CD28 Costimulatory Domain-Targeted Mutations Enhance Chimeric Antigen Receptor T-cell Function.
Authors: Boucher JC; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida., Li G; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida., Kotani H; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida., Cabral ML; Department of Cell Biology, Microbiology, and Molecular Biology, College of Arts and Sciences, University of South Florida, Tampa, Florida., Morrissey D; Morsani College of Medicine, University of South Florida Health, Tampa, Florida., Lee SB; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida.; Cancer Biology Ph.D. Program, University of South Florida, Tampa, Florida., Spitler K; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida., Beatty NJ; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida.; Cancer Biology Ph.D. Program, University of South Florida, Tampa, Florida., Cervantes EV; Morsani College of Medicine, University of South Florida Health, Tampa, Florida., Shrestha B; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida., Yu B; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida., Kazi A; Drug Discovery Program, H. Lee Moffitt Cancer Center, Tampa, Florida., Wang X; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center, Tampa, Florida., Sebti SM; Drug Discovery Program, H. Lee Moffitt Cancer Center, Tampa, Florida., Davila ML; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida. marco.davila@moffitt.org.; Morsani College of Medicine, University of South Florida Health, Tampa, Florida.
Source: Cancer immunology research [Cancer Immunol Res] 2021 Jan; Vol. 9 (1), pp. 62-74. Date of Electronic Publication: 2020 Nov 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CD28 Costimulatory Domain-Targeted Mutations Enhance Chimeric Antigen Receptor T-cell Function.
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  Data: <searchLink fieldCode="AU" term="%22Boucher+JC%22">Boucher JC</searchLink>; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Li+G%22">Li G</searchLink>; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Kotani+H%22">Kotani H</searchLink>; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Cabral+ML%22">Cabral ML</searchLink>; Department of Cell Biology, Microbiology, and Molecular Biology, College of Arts and Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Morrissey+D%22">Morrissey D</searchLink>; Morsani College of Medicine, University of South Florida Health, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Lee+SB%22">Lee SB</searchLink>; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida.; Cancer Biology Ph.D. Program, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Spitler+K%22">Spitler K</searchLink>; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Beatty+NJ%22">Beatty NJ</searchLink>; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida.; Cancer Biology Ph.D. Program, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Cervantes+EV%22">Cervantes EV</searchLink>; Morsani College of Medicine, University of South Florida Health, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Shrestha+B%22">Shrestha B</searchLink>; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Yu+B%22">Yu B</searchLink>; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Kazi+A%22">Kazi A</searchLink>; Drug Discovery Program, H. Lee Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Sebti+SM%22">Sebti SM</searchLink>; Drug Discovery Program, H. Lee Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Davila+ML%22">Davila ML</searchLink>; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Division of Clinical Science, H. Lee Moffitt Cancer Center, Tampa, Florida. marco.davila@moffitt.org.; Morsani College of Medicine, University of South Florida Health, Tampa, Florida.
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  Data: <searchLink fieldCode="JN" term="%22101614637%22">Cancer immunology research</searchLink> [Cancer Immunol Res] 2021 Jan; Vol. 9 (1), pp. 62-74. <i>Date of Electronic Publication: </i>2020 Nov 13.
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              Text: 2021 Jan
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