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Improving target assessment in biomedical research: the GOT-IT recommendations.

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Title: Improving target assessment in biomedical research: the GOT-IT recommendations.
Authors: Emmerich CH; PAASP GmbH, Heidelberg, Germany. christoph.emmerich@paasp.net., Gamboa LM; Department of Experimental Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.; QUEST Center for Transforming Biomedical Research, Berlin Institute of Health, Berlin, Germany., Hofmann MCJ; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Branch for Translational Medicine & Pharmacology TMP, Frankfurt am Main, Germany., Bonin-Andresen M; Department of Experimental Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany., Arbach O; Department of Experimental Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.; SPARK-Validation Fund, Berlin Institute of Health, Berlin, Germany., Schendel P; Department of Experimental Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany., Gerlach B; PAASP GmbH, Heidelberg, Germany., Hempel K; Boehringer-Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Bespalov A; PAASP GmbH, Heidelberg, Germany.; Valdman Institute of Pharmacology, Pavlov Medical University, St. Petersburg, Russia., Dirnagl U; Department of Experimental Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.; QUEST Center for Transforming Biomedical Research, Berlin Institute of Health, Berlin, Germany., Parnham MJ; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Branch for Translational Medicine & Pharmacology TMP, Frankfurt am Main, Germany.; Faculty of Biochemistry, Chemistry & Pharmacy, J.W. Goethe University Frankfurt, Frankfurt am Main, Germany.
Source: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2021 Jan; Vol. 20 (1), pp. 64-81. Date of Electronic Publication: 2020 Nov 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124171 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-1784 (Electronic) Linking ISSN: 14741776 NLM ISO Abbreviation: Nat Rev Drug Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Emmerich+CH%22">Emmerich CH</searchLink>; PAASP GmbH, Heidelberg, Germany. christoph.emmerich@paasp.net.<br /><searchLink fieldCode="AU" term="%22Gamboa+LM%22">Gamboa LM</searchLink>; Department of Experimental Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.; QUEST Center for Transforming Biomedical Research, Berlin Institute of Health, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hofmann+MCJ%22">Hofmann MCJ</searchLink>; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Branch for Translational Medicine & Pharmacology TMP, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Bonin-Andresen+M%22">Bonin-Andresen M</searchLink>; Department of Experimental Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Arbach+O%22">Arbach O</searchLink>; Department of Experimental Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.; SPARK-Validation Fund, Berlin Institute of Health, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Schendel+P%22">Schendel P</searchLink>; Department of Experimental Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Gerlach+B%22">Gerlach B</searchLink>; PAASP GmbH, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Hempel+K%22">Hempel K</searchLink>; Boehringer-Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.<br /><searchLink fieldCode="AU" term="%22Bespalov+A%22">Bespalov A</searchLink>; PAASP GmbH, Heidelberg, Germany.; Valdman Institute of Pharmacology, Pavlov Medical University, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Dirnagl+U%22">Dirnagl U</searchLink>; Department of Experimental Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.; QUEST Center for Transforming Biomedical Research, Berlin Institute of Health, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Parnham+MJ%22">Parnham MJ</searchLink>; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Branch for Translational Medicine & Pharmacology TMP, Frankfurt am Main, Germany.; Faculty of Biochemistry, Chemistry & Pharmacy, J.W. Goethe University Frankfurt, Frankfurt am Main, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101124171%22">Nature reviews. Drug discovery</searchLink> [Nat Rev Drug Discov] 2021 Jan; Vol. 20 (1), pp. 64-81. <i>Date of Electronic Publication: </i>2020 Nov 16.
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