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GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates.

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Title: GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates.
Authors: Breen DM; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA. Electronic address: danna.breen@pfizer.com., Kim H; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Bennett D; Biostatistics, Early Clinical Development, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Calle RA; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Collins S; Biostatistics, Early Clinical Development, Pfizer R&D UK Limited, Ramsgate Road, Sandwich, Kent, UK., Esquejo RM; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., He T; Biomedicine Design, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Joaquim S; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Joyce A; Biomedicine Design, Pfizer Inc., 1 Burtt Road, Andover, MA, USA., Lambert M; Biomedicine Design, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Lin L; Biomedicine Design, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Pettersen B; Drug Safety Research and Development, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Qiao S; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Rossulek M; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Weber G; Biomedicine Design, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Wu Z; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Zhang BB; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Birnbaum MJ; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
Source: Cell metabolism [Cell Metab] 2020 Dec 01; Vol. 32 (6), pp. 938-950.e6. Date of Electronic Publication: 2020 Nov 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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              Text: 2020 Dec 01
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