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A marine microbiome antifungal targets urgent-threat drug-resistant fungi.

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Title: A marine microbiome antifungal targets urgent-threat drug-resistant fungi.
Authors: Zhang F; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA., Zhao M; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA., Braun DR; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA., Ericksen SS; Small Molecule Screening Facility, University of Wisconsin Carbone Cancer Center, Madison, WI, USA., Piotrowski JS; Yumanity Therapeutics, Cambridge, MA, USA., Nelson J; Yumanity Therapeutics, Cambridge, MA, USA., Peng J; Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Ananiev GE; Small Molecule Screening Facility, University of Wisconsin Carbone Cancer Center, Madison, WI, USA., Chanana S; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA., Barns K; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA., Fossen J; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA., Sanchez H; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA., Chevrette MG; Department of Genetics, University of Wisconsin-Madison, Madison, WI, USA.; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Institute for Discovery and Department of Plant Pathology, University of Wisconsin-Madison, Madison, WI, USA., Guzei IA; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Zhao C; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA., Guo L; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA., Tang W; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA., Currie CR; Department of Genetics, University of Wisconsin-Madison, Madison, WI, USA.; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA., Rajski SR; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA., Audhya A; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Andes DR; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA. tim.bugni@wisc.edu dra@medicine.wisc.edu., Bugni TS; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA. tim.bugni@wisc.edu dra@medicine.wisc.edu.
Source: Science (New York, N.Y.) [Science] 2020 Nov 20; Vol. 370 (6519), pp. 974-978.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+M%22">Zhao M</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Braun+DR%22">Braun DR</searchLink>; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Ericksen+SS%22">Ericksen SS</searchLink>; Small Molecule Screening Facility, University of Wisconsin Carbone Cancer Center, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Piotrowski+JS%22">Piotrowski JS</searchLink>; Yumanity Therapeutics, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+J%22">Nelson J</searchLink>; Yumanity Therapeutics, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Peng+J%22">Peng J</searchLink>; Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Ananiev+GE%22">Ananiev GE</searchLink>; Small Molecule Screening Facility, University of Wisconsin Carbone Cancer Center, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Chanana+S%22">Chanana S</searchLink>; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Barns+K%22">Barns K</searchLink>; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Fossen+J%22">Fossen J</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Sanchez+H%22">Sanchez H</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Chevrette+MG%22">Chevrette MG</searchLink>; Department of Genetics, University of Wisconsin-Madison, Madison, WI, USA.; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Institute for Discovery and Department of Plant Pathology, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Guzei+IA%22">Guzei IA</searchLink>; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+C%22">Zhao C</searchLink>; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Guo+L%22">Guo L</searchLink>; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Tang+W%22">Tang W</searchLink>; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Currie+CR%22">Currie CR</searchLink>; Department of Genetics, University of Wisconsin-Madison, Madison, WI, USA.; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Rajski+SR%22">Rajski SR</searchLink>; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Audhya+A%22">Audhya A</searchLink>; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Andes+DR%22">Andes DR</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA. tim.bugni@wisc.edu dra@medicine.wisc.edu.<br /><searchLink fieldCode="AU" term="%22Bugni+TS%22">Bugni TS</searchLink>; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA. tim.bugni@wisc.edu dra@medicine.wisc.edu.
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