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An enolase inhibitor for the targeted treatment of ENO1-deleted cancers.

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Title: An enolase inhibitor for the targeted treatment of ENO1-deleted cancers.
Authors: Lin YH; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Satani N; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Institute of Stroke and Cerebrovascular Disease, University of Texas Health Science Center at Houston, Houston, TX, USA., Hammoudi N; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Yan VC; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Barekatain Y; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Khadka S; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Ackroyd JJ; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Georgiou DK; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Pham CD; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Arthur K; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Maxwell D; Institutional Analytics & Informatics, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Peng Z; Cardtronics, Inc, Houston, TX, USA., Leonard PG; Core for Biomolecular Structure and Function, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Czako B; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Pisaneschi F; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Mandal P; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Sun Y; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zielinski R; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Pando SC; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wang X; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Tran T; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Xu Q; Pharmaceutical Science Facility, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wu Q; Pharmaceutical Science Facility, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Jiang Y; Pharmaceutical Science Facility, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kang Z; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Asara JM; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA., Priebe W; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Bornmann W; Director of Drug Discovery and Development, Advanced Organic Synthesis LLC, Houston, Texas, USA., Marszalek JR; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA., DePinho RA; Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Muller FL; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA. aettius@aol.com.
Source: Nature metabolism [Nat Metab] 2020 Dec; Vol. 2 (12), pp. 1413-1426. Date of Electronic Publication: 2020 Nov 23.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE
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  Data: An enolase inhibitor for the targeted treatment of ENO1-deleted cancers.
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  Data: <searchLink fieldCode="AU" term="%22Lin+YH%22">Lin YH</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Satani+N%22">Satani N</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Institute of Stroke and Cerebrovascular Disease, University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Hammoudi+N%22">Hammoudi N</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Yan+VC%22">Yan VC</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Barekatain+Y%22">Barekatain Y</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Khadka+S%22">Khadka S</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ackroyd+JJ%22">Ackroyd JJ</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Georgiou+DK%22">Georgiou DK</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Pham+CD%22">Pham CD</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Arthur+K%22">Arthur K</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Maxwell+D%22">Maxwell D</searchLink>; Institutional Analytics & Informatics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Peng+Z%22">Peng Z</searchLink>; Cardtronics, Inc, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Leonard+PG%22">Leonard PG</searchLink>; Core for Biomolecular Structure and Function, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Czako+B%22">Czako B</searchLink>; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Pisaneschi+F%22">Pisaneschi F</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Mandal+P%22">Mandal P</searchLink>; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Zielinski+R%22">Zielinski R</searchLink>; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Pando+SC%22">Pando SC</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tran+T%22">Tran T</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Xu+Q%22">Xu Q</searchLink>; Pharmaceutical Science Facility, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Wu+Q%22">Wu Q</searchLink>; Pharmaceutical Science Facility, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; Pharmaceutical Science Facility, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kang+Z%22">Kang Z</searchLink>; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Asara+JM%22">Asara JM</searchLink>; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Priebe+W%22">Priebe W</searchLink>; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Bornmann+W%22">Bornmann W</searchLink>; Director of Drug Discovery and Development, Advanced Organic Synthesis LLC, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Marszalek+JR%22">Marszalek JR</searchLink>; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22DePinho+RA%22">DePinho RA</searchLink>; Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Muller+FL%22">Muller FL</searchLink>; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA. aettius@aol.com.
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  Data: <searchLink fieldCode="JN" term="%22101736592%22">Nature metabolism</searchLink> [Nat Metab] 2020 Dec; Vol. 2 (12), pp. 1413-1426. <i>Date of Electronic Publication: </i>2020 Nov 23.
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