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Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.

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Title: Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.
Authors: Miller-Vedam LE; Molecular, Cellular, and Computational Biophysics Graduate Program, University of California, San Francisco, San Francisco, United States.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States.; Department of Biology, Whitehead Institute, MIT, Cambridge, United States.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Bräuning B; Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany., Popova KD; Department of Biology, Whitehead Institute, MIT, Cambridge, United States.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, United States., Schirle Oakdale NT; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Bonnar JL; Department of Biology, Whitehead Institute, MIT, Cambridge, United States.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Prabu JR; Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany., Boydston EA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Sevillano N; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, United States., Shurtleff MJ; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Stroud RM; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States., Craik CS; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, United States., Schulman BA; Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany., Frost A; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States., Weissman JS; Department of Biology, Whitehead Institute, MIT, Cambridge, United States.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, Chevy Chase, United States.
Source: ELife [Elife] 2020 Nov 25; Vol. 9. Date of Electronic Publication: 2020 Nov 25.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Video-Audio Media
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Miller-Vedam+LE%22">Miller-Vedam LE</searchLink>; Molecular, Cellular, and Computational Biophysics Graduate Program, University of California, San Francisco, San Francisco, United States.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States.; Department of Biology, Whitehead Institute, MIT, Cambridge, United States.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Bräuning+B%22">Bräuning B</searchLink>; Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Popova+KD%22">Popova KD</searchLink>; Department of Biology, Whitehead Institute, MIT, Cambridge, United States.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Schirle+Oakdale+NT%22">Schirle Oakdale NT</searchLink>; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Bonnar+JL%22">Bonnar JL</searchLink>; Department of Biology, Whitehead Institute, MIT, Cambridge, United States.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Prabu+JR%22">Prabu JR</searchLink>; Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Boydston+EA%22">Boydston EA</searchLink>; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Sevillano+N%22">Sevillano N</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Shurtleff+MJ%22">Shurtleff MJ</searchLink>; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Stroud+RM%22">Stroud RM</searchLink>; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Craik+CS%22">Craik CS</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Schulman+BA%22">Schulman BA</searchLink>; Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Frost+A%22">Frost A</searchLink>; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Weissman+JS%22">Weissman JS</searchLink>; Department of Biology, Whitehead Institute, MIT, Cambridge, United States.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, Chevy Chase, United States.
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