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Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report.

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Title: Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report.
Authors: Dominguez-Valentin M; Department of Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo, Norway. mev.dominguez.valentin@rr-research.no., Crosbie EJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester and St Mary's Hospital, Manchester, UK. Emma.Crosbie@manchester.ac.uk.; Directorate of Gynaecology, Manchester University NHS Foundation Trust, Manchester, UK. Emma.Crosbie@manchester.ac.uk., Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany., Aretz S; Institute of Human Genetics, University of Bonn, Bonn, Germany.; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany., Macrae F; Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, Australia.; Department of Medicine, Melbourne University, Melbourne, Australia., Winship I; Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, Australia.; Department of Medicine, Melbourne University, Melbourne, Australia., Capella G; Hereditary Cancer Program, Institut Catal. d'Oncologia-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain., Thomas H; St Mark's Hospital, Department of Surgery and Cancer, Imperial College London, London, UK., Nakken S; Department of Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo, Norway.; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Hovig E; Department of Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo, Norway.; Department of Informatics, University of Oslo, Oslo, Norway., Nielsen M; Leids Universitair Medisch Centrum, Leiden, Netherlands., Sijmons RH; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Bertario L; IEO, European Institute of Oncology IRCCS, Milan, Italy.; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Bonanni B; IEO, European Institute of Oncology IRCCS, Milan, Italy., Tibiletti MG; Ospedale di Circolo ASST Settelaghi, Centro di Ricerca tumori eredo-familiari, Università dell'Insubria, Varese, Italy., Cavestro GM; Gastroenterology and Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, San Raffaele Scientific Institute, Milan, Italy., Mints M; Department of Women's and Children's health, Division of Obstetrics and Gyneacology, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden., Gluck N; Tel-Aviv Sourasky Medical Center, Research Center for Digestive Disorders and Liver Diseases, Tel-Aviv, Israel.; Department of Gastroenterology, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel., Katz L; High Risk and GI Cancer prevention Clinic, Gastro-Oncology Unit, The Department of Gastroenterology, Sheba Medical Center, Tel-Aviv, Israel., Heinimann K; Medical Genetics, Institute for Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland., Vaccaro CA; Hereditary Cancer Program (PROCANHE) Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.; Instituto de Ciencias Básicas y Medicina Experimental (ICBME)-Instituto Universitario (IU)-Hospital, Buenos Aires, Argentina., Green K; Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Lalloo F; Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Hill J; Department of Surgery, Manchester University Hospitals NHS Foundation Trust and University of Manchester, Manchester, UK., Schmiegel W; Department of Medicine, Knappschaftskrankenhaus, Ruhr-University Bochum, Bochum, Germany., Vangala D; Department of Medicine, Knappschaftskrankenhaus, Ruhr-University Bochum, Bochum, Germany., Perne C; Institute of Human Genetics, University of Bonn, Bonn, Germany.; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany., Strauß HG; Department of Gynaecology, University Clinics, Martin-Luther University, Halle-Wittenberg, Germany., Tecklenburg J; Institute of Human Genetics, Hannover Medical School, Hannover, Germany., Holinski-Feder E; Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany.; MGZ Medical Genetics Center, Munich, Germany., Steinke-Lange V; Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany.; MGZ Medical Genetics Center, Munich, Germany., Mecklin JP; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.; Department of Surgery, Central Finland Health Care District, Jyväskylä, Finland., Plazzer JP; The Royal Melbourne Hospital, Melbourne, Australia., Pineda M; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain., Navarro M; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain., Vidal JB; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain., Kariv R; Department of Gastroenterology, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel., Rosner G; Department of Gastroenterology, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel., Piñero TA; Instituto de Ciencias Básicas y Medicina Experimental (ICBME)-Instituto Universitario (IU)-Hospital, Buenos Aires, Argentina., Gonzalez ML; Instituto de Ciencias Básicas y Medicina Experimental (ICBME)-Instituto Universitario (IU)-Hospital, Buenos Aires, Argentina., Kalfayan P; Instituto de Ciencias Básicas y Medicina Experimental (ICBME)-Instituto Universitario (IU)-Hospital, Buenos Aires, Argentina., Ryan N; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester and St Mary's Hospital, Manchester, UK., Ten Broeke SW; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Jenkins MA; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia., Sunde L; Department of Clinical Genetics, Aalborg University Hospital, Aalborg, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Bernstein I; Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark., Burn J; Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Greenblatt M; University of Vermont, Larner College of Medicine, Burlington, VT 05405, USA., de Vos Tot Nederveen Cappel WH; Department of Gastroenterology and Hepatology, Isala Clinics, Zwolle, The Netherlands., Della Valle A; Grupo Colaborativo Uruguayo, Investigación de Afecciones Oncológicas Hereditarias (GCU), Hospital Fuerzas Armadas, Montevideo, Uruguay., Lopez-Koestner F; Lab. Oncología y Genética Molecular, Unidad de coloproctología Clínica Las Condes, Santiago, Chile., Alvarez K; Lab. Oncología y Genética Molecular, Unidad de coloproctología Clínica Las Condes, Santiago, Chile., Büttner R; Institute of Pathology, University of Cologne, Cologne, Germany., Görgens H; Department of Surgery, Technische Universität Dresden, Dresden, Germany., Morak M; Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany.; MGZ Medical Genetics Center, Munich, Germany., Holzapfel S; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany.; Department of Internal Medicine I, University Hospital Bonn; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany., Hüneburg R; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany.; Department of Internal Medicine I, University Hospital Bonn; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany., von Knebel Doeberitz M; Department of Applied Tumour Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.; Cooperation Unit Applied Tumour Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Loeffler M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany., Rahner N; Institute of Human Genetics, Medical School, Heinrich Heine University, Duesseldorf, Germany., Weitz J; Department of Surgery, Technische Universität Dresden, Dresden, Germany., Pylvänäinen K; Department of Education and Science, Central Finland Health Care District, yväskylä, Finland., Renkonen-Sinisalo L; Department of Obstetrics and Gynecology and Tays Cancer Centre, Tampere University Hospital and Tampere University, Tampere, Finland., Lepistö A; Department of Gastrointestinal Surgery, Helsinki University Central Hospital, Applied Tumour Genomics Research Program, University of Helsinki, Helsinki, Finland., Auranen A; Department of Obstetrics and Gynecology and Tays Cancer Centre, Tampere University Hospital and Tampere University, Tampere, Finland., Hopper JL; Department of Health Science Research, Mayo Clinic Arizona, Phoenix, AZ, USA., Win AK; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia., Haile RW; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University, Stanford, USA., Lindor NM; Department of Health Science Research, Mayo Clinic Arizona, Phoenix, AZ, USA., Gallinger S; Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada., Le Marchand L; University of Hawaii Cancer Center, Honolulu, HI, USA., Newcomb PA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Figueiredo JC; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Thibodeau SN; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Therkildsen C; The Danish HNPCC register, Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark., Okkels H; Department of Molecular Diagnostics, Aalborg University Hospital, Aalborg, Denmark., Ketabi Z; Dept. of Obstetrics and Gynaecology, Copenhagen University Hospital, Rigshospitalet, Denmark., Denton OG; Institute of Medical Genetics, Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, UK., Rødland EA; Department of Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo, Norway., Vasen H; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, The Netherlands., Neffa F; Institute of Pathology, University of Cologne, Cologne, Germany., Esperon P; Institute of Pathology, University of Cologne, Cologne, Germany., Tjandra D; Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melborne, Australia.; Department of Medicine, Melbourne University, Melborne, Australia., Möslein G; Surgical Center for Hereditary Tumors, Ev. Bethesda Khs Duisburg, University Witten-Herdecke, Herdecke, Germany., Sampson JR; Institute of Medical Genetics, Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, UK., Evans DG; Division of Evolution and Genomic Medicine, University of Manchester, Manchester, UK.; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Seppälä TT; Department of Gastrointestinal Surgery, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland.; Department of Surgical Oncology, Johns Hopkins Hospital, Baltimore, MD, USA., Møller P; Department of Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo, Norway. moller.pal@gmail.com.
Source: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2021 Apr; Vol. 23 (4), pp. 705-712. Date of Electronic Publication: 2020 Dec 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9815831 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0366 (Electronic) Linking ISSN: 10983600 NLM ISO Abbreviation: Genet Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
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PubType: Academic Journal
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Items – Name: Title
  Label: Title
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  Data: Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Dominguez-Valentin+M%22">Dominguez-Valentin M</searchLink>; Department of Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo, Norway. mev.dominguez.valentin@rr-research.no.<br /><searchLink fieldCode="AU" term="%22Crosbie+EJ%22">Crosbie EJ</searchLink>; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester and St Mary's Hospital, Manchester, UK. Emma.Crosbie@manchester.ac.uk.; Directorate of Gynaecology, Manchester University NHS Foundation Trust, Manchester, UK. Emma.Crosbie@manchester.ac.uk.<br /><searchLink fieldCode="AU" term="%22Engel+C%22">Engel C</searchLink>; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Aretz+S%22">Aretz S</searchLink>; Institute of Human Genetics, University of Bonn, Bonn, Germany.; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Macrae+F%22">Macrae F</searchLink>; Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, Australia.; Department of Medicine, Melbourne University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Winship+I%22">Winship I</searchLink>; Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, Australia.; Department of Medicine, Melbourne University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Capella+G%22">Capella G</searchLink>; Hereditary Cancer Program, Institut Catal. d'Oncologia-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Thomas+H%22">Thomas H</searchLink>; St Mark's Hospital, Department of Surgery and Cancer, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Nakken+S%22">Nakken S</searchLink>; Department of Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo, Norway.; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Hovig+E%22">Hovig E</searchLink>; Department of Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo, Norway.; Department of Informatics, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Nielsen+M%22">Nielsen M</searchLink>; Leids Universitair Medisch Centrum, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sijmons+RH%22">Sijmons RH</searchLink>; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bertario+L%22">Bertario L</searchLink>; IEO, European Institute of Oncology IRCCS, Milan, Italy.; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bonanni+B%22">Bonanni B</searchLink>; IEO, European Institute of Oncology IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tibiletti+MG%22">Tibiletti MG</searchLink>; Ospedale di Circolo ASST Settelaghi, Centro di Ricerca tumori eredo-familiari, Università dell'Insubria, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Cavestro+GM%22">Cavestro GM</searchLink>; Gastroenterology and Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mints+M%22">Mints M</searchLink>; Department of Women's and Children's health, Division of Obstetrics and Gyneacology, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Gluck+N%22">Gluck N</searchLink>; Tel-Aviv Sourasky Medical Center, Research Center for Digestive Disorders and Liver Diseases, Tel-Aviv, Israel.; Department of Gastroenterology, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Katz+L%22">Katz L</searchLink>; High Risk and GI Cancer prevention Clinic, Gastro-Oncology Unit, The Department of Gastroenterology, Sheba Medical Center, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Heinimann+K%22">Heinimann K</searchLink>; Medical Genetics, Institute for Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vaccaro+CA%22">Vaccaro CA</searchLink>; Hereditary Cancer Program (PROCANHE) Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.; Instituto de Ciencias Básicas y Medicina Experimental (ICBME)-Instituto Universitario (IU)-Hospital, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Green+K%22">Green K</searchLink>; Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Lalloo+F%22">Lalloo F</searchLink>; Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Hill+J%22">Hill J</searchLink>; Department of Surgery, Manchester University Hospitals NHS Foundation Trust and University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Schmiegel+W%22">Schmiegel W</searchLink>; Department of Medicine, Knappschaftskrankenhaus, Ruhr-University Bochum, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Vangala+D%22">Vangala D</searchLink>; Department of Medicine, Knappschaftskrankenhaus, Ruhr-University Bochum, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Perne+C%22">Perne C</searchLink>; Institute of Human Genetics, University of Bonn, Bonn, Germany.; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Strauß+HG%22">Strauß HG</searchLink>; Department of Gynaecology, University Clinics, Martin-Luther University, Halle-Wittenberg, Germany.<br /><searchLink fieldCode="AU" term="%22Tecklenburg+J%22">Tecklenburg J</searchLink>; Institute of Human Genetics, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Holinski-Feder+E%22">Holinski-Feder E</searchLink>; Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany.; MGZ Medical Genetics Center, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Steinke-Lange+V%22">Steinke-Lange V</searchLink>; Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany.; MGZ Medical Genetics Center, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Mecklin+JP%22">Mecklin JP</searchLink>; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.; Department of Surgery, Central Finland Health Care District, Jyväskylä, Finland.<br /><searchLink fieldCode="AU" term="%22Plazzer+JP%22">Plazzer JP</searchLink>; The Royal Melbourne Hospital, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Pineda+M%22">Pineda M</searchLink>; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Navarro+M%22">Navarro M</searchLink>; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Vidal+JB%22">Vidal JB</searchLink>; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Kariv+R%22">Kariv R</searchLink>; Department of Gastroenterology, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Rosner+G%22">Rosner G</searchLink>; Department of Gastroenterology, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Piñero+TA%22">Piñero TA</searchLink>; Instituto de Ciencias Básicas y Medicina Experimental (ICBME)-Instituto Universitario (IU)-Hospital, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Gonzalez+ML%22">Gonzalez ML</searchLink>; Instituto de Ciencias Básicas y Medicina Experimental (ICBME)-Instituto Universitario (IU)-Hospital, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Kalfayan+P%22">Kalfayan P</searchLink>; Instituto de Ciencias Básicas y Medicina Experimental (ICBME)-Instituto Universitario (IU)-Hospital, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Ryan+N%22">Ryan N</searchLink>; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester and St Mary's Hospital, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Ten+Broeke+SW%22">Ten Broeke SW</searchLink>; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Jenkins+MA%22">Jenkins MA</searchLink>; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Sunde+L%22">Sunde L</searchLink>; Department of Clinical Genetics, Aalborg University Hospital, Aalborg, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Bernstein+I%22">Bernstein I</searchLink>; Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Burn+J%22">Burn J</searchLink>; Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Greenblatt+M%22">Greenblatt M</searchLink>; University of Vermont, Larner College of Medicine, Burlington, VT 05405, USA.<br /><searchLink fieldCode="AU" term="%22de+Vos+Tot+Nederveen+Cappel+WH%22">de Vos Tot Nederveen Cappel WH</searchLink>; Department of Gastroenterology and Hepatology, Isala Clinics, Zwolle, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Della+Valle+A%22">Della Valle A</searchLink>; Grupo Colaborativo Uruguayo, Investigación de Afecciones Oncológicas Hereditarias (GCU), Hospital Fuerzas Armadas, Montevideo, Uruguay.<br /><searchLink fieldCode="AU" term="%22Lopez-Koestner+F%22">Lopez-Koestner F</searchLink>; Lab. Oncología y Genética Molecular, Unidad de coloproctología Clínica Las Condes, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Alvarez+K%22">Alvarez K</searchLink>; Lab. Oncología y Genética Molecular, Unidad de coloproctología Clínica Las Condes, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Büttner+R%22">Büttner R</searchLink>; Institute of Pathology, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Görgens+H%22">Görgens H</searchLink>; Department of Surgery, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Morak+M%22">Morak M</searchLink>; Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany.; MGZ Medical Genetics Center, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Holzapfel+S%22">Holzapfel S</searchLink>; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany.; Department of Internal Medicine I, University Hospital Bonn; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Hüneburg+R%22">Hüneburg R</searchLink>; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany.; Department of Internal Medicine I, University Hospital Bonn; National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22von+Knebel+Doeberitz+M%22">von Knebel Doeberitz M</searchLink>; Department of Applied Tumour Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.; Cooperation Unit Applied Tumour Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Loeffler+M%22">Loeffler M</searchLink>; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Rahner+N%22">Rahner N</searchLink>; Institute of Human Genetics, Medical School, Heinrich Heine University, Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Weitz+J%22">Weitz J</searchLink>; Department of Surgery, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Pylvänäinen+K%22">Pylvänäinen K</searchLink>; Department of Education and Science, Central Finland Health Care District, yväskylä, Finland.<br /><searchLink fieldCode="AU" term="%22Renkonen-Sinisalo+L%22">Renkonen-Sinisalo L</searchLink>; Department of Obstetrics and Gynecology and Tays Cancer Centre, Tampere University Hospital and Tampere University, Tampere, Finland.<br /><searchLink fieldCode="AU" term="%22Lepistö+A%22">Lepistö A</searchLink>; Department of Gastrointestinal Surgery, Helsinki University Central Hospital, Applied Tumour Genomics Research Program, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Auranen+A%22">Auranen A</searchLink>; Department of Obstetrics and Gynecology and Tays Cancer Centre, Tampere University Hospital and Tampere University, Tampere, Finland.<br /><searchLink fieldCode="AU" term="%22Hopper+JL%22">Hopper JL</searchLink>; Department of Health Science Research, Mayo Clinic Arizona, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Win+AK%22">Win AK</searchLink>; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Haile+RW%22">Haile RW</searchLink>; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University, Stanford, USA.<br /><searchLink fieldCode="AU" term="%22Lindor+NM%22">Lindor NM</searchLink>; Department of Health Science Research, Mayo Clinic Arizona, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Gallinger+S%22">Gallinger S</searchLink>; Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Le+Marchand+L%22">Le Marchand L</searchLink>; University of Hawaii Cancer Center, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Newcomb+PA%22">Newcomb PA</searchLink>; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Figueiredo+JC%22">Figueiredo JC</searchLink>; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Thibodeau+SN%22">Thibodeau SN</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Therkildsen+C%22">Therkildsen C</searchLink>; The Danish HNPCC register, Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark.<br /><searchLink fieldCode="AU" term="%22Okkels+H%22">Okkels H</searchLink>; Department of Molecular Diagnostics, Aalborg University Hospital, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Ketabi+Z%22">Ketabi Z</searchLink>; Dept. of Obstetrics and Gynaecology, Copenhagen University Hospital, Rigshospitalet, Denmark.<br /><searchLink fieldCode="AU" term="%22Denton+OG%22">Denton OG</searchLink>; Institute of Medical Genetics, Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Rødland+EA%22">Rødland EA</searchLink>; Department of Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Vasen+H%22">Vasen H</searchLink>; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Neffa+F%22">Neffa F</searchLink>; Institute of Pathology, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Esperon+P%22">Esperon P</searchLink>; Institute of Pathology, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Tjandra+D%22">Tjandra D</searchLink>; Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melborne, Australia.; Department of Medicine, Melbourne University, Melborne, Australia.<br /><searchLink fieldCode="AU" term="%22Möslein+G%22">Möslein G</searchLink>; Surgical Center for Hereditary Tumors, Ev. Bethesda Khs Duisburg, University Witten-Herdecke, Herdecke, Germany.<br /><searchLink fieldCode="AU" term="%22Sampson+JR%22">Sampson JR</searchLink>; Institute of Medical Genetics, Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Evans+DG%22">Evans DG</searchLink>; Division of Evolution and Genomic Medicine, University of Manchester, Manchester, UK.; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Seppälä+TT%22">Seppälä TT</searchLink>; Department of Gastrointestinal Surgery, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland.; Department of Surgical Oncology, Johns Hopkins Hospital, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Møller+P%22">Møller P</searchLink>; Department of Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo, Norway. moller.pal@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%229815831%22">Genetics in medicine : official journal of the American College of Medical Genetics</searchLink> [Genet Med] 2021 Apr; Vol. 23 (4), pp. 705-712. <i>Date of Electronic Publication: </i>2020 Dec 01.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9815831 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1530-0366 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210983600%22">10983600 </searchLink><i>NLM ISO Abbreviation: </i>Genet Med <i>Subsets: </i>MEDLINE
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      – TitleFull: Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report.
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