View in EDS HTML Full Text PDF Full Text

Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease.

Saved in:
Bibliographic Details
Title: Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease.
Authors: Yuede CM; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Wallace CE; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Davis TA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Gardiner WD; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Hettinger JC; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Edwards HM; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Hendrix RD; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Doherty BM; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Yuede KM; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Burstein ES; ACADIA Pharmaceuticals Inc, San Diego, CA, USA., Cirrito JR; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.
Source: Journal of neurochemistry [J Neurochem] 2021 Mar; Vol. 156 (5), pp. 658-673. Date of Electronic Publication: 2021 Jan 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 33278025
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Pimavanserin, a 5HT<subscript>2A</subscript> receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Yuede+CM%22">Yuede CM</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Wallace+CE%22">Wallace CE</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Davis+TA%22">Davis TA</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Gardiner+WD%22">Gardiner WD</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Hettinger+JC%22">Hettinger JC</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Edwards+HM%22">Edwards HM</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Hendrix+RD%22">Hendrix RD</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Doherty+BM%22">Doherty BM</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Yuede+KM%22">Yuede KM</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Burstein+ES%22">Burstein ES</searchLink>; ACADIA Pharmaceuticals Inc, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cirrito+JR%22">Cirrito JR</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%222985190R%22">Journal of neurochemistry</searchLink> [J Neurochem] 2021 Mar; Vol. 156 (5), pp. 658-673. <i>Date of Electronic Publication: </i>2021 Jan 10.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+on+behalf+of+the+International+Society+for+Neurochemistry%22">Wiley on behalf of the International Society for Neurochemistry </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985190R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-4159 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223042%22">00223042 </searchLink><i>NLM ISO Abbreviation: </i>J Neurochem <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=33278025
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/jnc.15260
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 658
    Titles:
      – TitleFull: Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Yuede CM
      – PersonEntity:
          Name:
            NameFull: Wallace CE
      – PersonEntity:
          Name:
            NameFull: Davis TA
      – PersonEntity:
          Name:
            NameFull: Gardiner WD
      – PersonEntity:
          Name:
            NameFull: Hettinger JC
      – PersonEntity:
          Name:
            NameFull: Edwards HM
      – PersonEntity:
          Name:
            NameFull: Hendrix RD
      – PersonEntity:
          Name:
            NameFull: Doherty BM
      – PersonEntity:
          Name:
            NameFull: Yuede KM
      – PersonEntity:
          Name:
            NameFull: Burstein ES
      – PersonEntity:
          Name:
            NameFull: Cirrito JR
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: 2021 Mar
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 1471-4159
          Numbering:
            – Type: volume
              Value: 156
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Journal of neurochemistry
              Type: main
ResultId 1