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Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues.

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Title: Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues.
Authors: Zhang W; Université de Paris, BFA, UMR 8251, CNRS, F-75013, Paris, France., Berthelet J; Université de Paris, BFA, UMR 8251, CNRS, F-75013, Paris, France; Université de Paris, CEDC, UMR 7216, CNRS, F-75013, Paris, France., Michail C; Université de Paris, BFA, UMR 8251, CNRS, F-75013, Paris, France., Bui LC; Université de Paris, BFA, UMR 8251, CNRS, F-75013, Paris, France., Gou P; Université de Paris, Institut de Recherche Saint-Louis, UMRS 1131, INSERM, F-75010, Paris, France., Liu R; Université de Paris, BFA, UMR 8251, CNRS, F-75013, Paris, France., Duval R; Université de Paris, BIGR, UMRS 1134, INSERM, F-75015, Paris, France., Renault J; Université de Paris, BFA, UMR 8251, CNRS, F-75013, Paris, France., Dupret JM; Université de Paris, BFA, UMR 8251, CNRS, F-75013, Paris, France., Guidez F; Université de Paris, Institut de Recherche Saint-Louis, UMRS 1131, INSERM, F-75010, Paris, France., Chomienne C; Université de Paris, Institut de Recherche Saint-Louis, UMRS 1131, INSERM, F-75010, Paris, France; Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France., Rodrigues Lima F; Université de Paris, BFA, UMR 8251, CNRS, F-75013, Paris, France. Electronic address: fernando.rodrigues-lima@u-paris.fr.
Source: Free radical biology & medicine [Free Radic Biol Med] 2021 Jan; Vol. 162, pp. 27-37. Date of Electronic Publication: 2020 Dec 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-4596
DOI:10.1016/j.freeradbiomed.2020.11.027