Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis.
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| Title: | Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis. |
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| Authors: | Leimkühler NB; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands., Gleitz HFE; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands., Ronghui L; Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Aachen 52074 Germany., Snoeren IAM; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands., Fuchs SNR; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands., Nagai JS; Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Aachen 52074 Germany., Banjanin B; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands., Lam KH; Department of Pathology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands., Vogl T; Institute of Immunology, University of Münster, Münster 49148, Germany., Kuppe C; Division of Nephrology and Clinical Immunology, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany., Stalmann USA; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands., Büsche G; Institute of Pathology, Hannover Medical School, Hannover 30625, Germany., Kreipe H; Institute of Pathology, Hannover Medical School, Hannover 30625, Germany., Gütgemann I; Institute of Pathology, University of Bonn, Bonn 53127, Germany., Krebs P; Institute of Pathology, University of Bern, Bern 3012, Switzerland., Banz Y; Institute of Pathology, University of Bern, Bern 3012, Switzerland., Boor P; Institute of Pathology, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany., Tai EW; Institute of Pathology, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany., Brümmendorf TH; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany., Koschmieder S; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany., Crysandt M; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany., Bindels E; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands., Kramann R; Division of Nephrology and Clinical Immunology, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen 52074, Germany., Costa IG; Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Aachen 52074 Germany., Schneider RK; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands; Department of Cell Biology, Institute for Biomedical Engineering, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany; Oncode Institute, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands. Electronic address: reschneider@ukaachen.de. |
| Source: | Cell stem cell [Cell Stem Cell] 2021 Apr 01; Vol. 28 (4), pp. 637-652.e8. Date of Electronic Publication: 2020 Dec 09. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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