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Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.

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Title: Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.
Authors: Coni S; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy., Serrao SM; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy., Yurtsever ZN; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy., Di Magno L; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy., Bordone R; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy., Bertani C; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy., Licursi V; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy., Ianniello Z; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy., Infante P; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161, Rome, Italy., Moretti M; Department of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy., Petroni M; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy., Guerrieri F; Cancer Research Center of Lyon (CRCL), UMR Inserm U1052/CNRS 5286, Lyon, France., Fatica A; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy., Macone A; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy., De Smaele E; Department of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy., Di Marcotullio L; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy.; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy., Giannini G; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy., Maroder M; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy., Agostinelli E; International Polyamines Foundation-ONLUS, Via del Forte Tiburtino 98, 00159, Rome, Italy.; Department of Sense Organs, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy., Canettieri G; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy. gianluca.canettieri@uniroma1.it.; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy. gianluca.canettieri@uniroma1.it.; International Polyamines Foundation-ONLUS, Via del Forte Tiburtino 98, 00159, Rome, Italy. gianluca.canettieri@uniroma1.it.
Source: Cell death & disease [Cell Death Dis] 2020 Dec 10; Vol. 11 (12), pp. 1045. Date of Electronic Publication: 2020 Dec 10.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
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  Data: Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.
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  Data: <searchLink fieldCode="AU" term="%22Coni+S%22">Coni S</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Serrao+SM%22">Serrao SM</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Yurtsever+ZN%22">Yurtsever ZN</searchLink>; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Magno+L%22">Di Magno L</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bordone+R%22">Bordone R</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bertani+C%22">Bertani C</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Licursi+V%22">Licursi V</searchLink>; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ianniello+Z%22">Ianniello Z</searchLink>; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Infante+P%22">Infante P</searchLink>; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Moretti+M%22">Moretti M</searchLink>; Department of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Petroni+M%22">Petroni M</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Guerrieri+F%22">Guerrieri F</searchLink>; Cancer Research Center of Lyon (CRCL), UMR Inserm U1052/CNRS 5286, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Fatica+A%22">Fatica A</searchLink>; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Macone+A%22">Macone A</searchLink>; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22De+Smaele+E%22">De Smaele E</searchLink>; Department of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Marcotullio+L%22">Di Marcotullio L</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy.; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Giannini+G%22">Giannini G</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Maroder+M%22">Maroder M</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Agostinelli+E%22">Agostinelli E</searchLink>; International Polyamines Foundation-ONLUS, Via del Forte Tiburtino 98, 00159, Rome, Italy.; Department of Sense Organs, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico 155, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Canettieri+G%22">Canettieri G</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy. gianluca.canettieri@uniroma1.it.; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, Viale Regina Elena 291, 00161, Rome, Italy. gianluca.canettieri@uniroma1.it.; International Polyamines Foundation-ONLUS, Via del Forte Tiburtino 98, 00159, Rome, Italy. gianluca.canettieri@uniroma1.it.
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