Synthesis and Biological Evaluation of (-) and (+)-Spiroleucettadine and Analogues.

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Title: Synthesis and Biological Evaluation of (-) and (+)-Spiroleucettadine and Analogues.
Authors: Badart MP; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand., Barnes EM; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand., Cording AP; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand., Gilmer SCL; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand., Billinghurst ID; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand., Edupuganti VVSR; School of Pharmacy, University of Otago, Dunedin, 9054, New Zealand., Lessene G; ACRF Chemical Biology Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3050, Australia.; Department of Pharmacology and Therapeutics, The University of Melbourne, Parkville, VIC 3050, Australia., Bland AR; Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9054, New Zealand., Bower RL; Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9054, New Zealand., Rana Z; Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9054, New Zealand., Ferguson SA; Department of Microbiology and Immunology, University of Otago, Dunedin, 9054, New Zealand., Opel Reading HK; Department of Biochemistry, University of Otago, Dunedin, 9054, New Zealand., Cook GM; Department of Microbiology and Immunology, University of Otago, Dunedin, 9054, New Zealand., Rosengren RJ; Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9054, New Zealand., Krause KL; Department of Biochemistry, University of Otago, Dunedin, 9054, New Zealand., Gamble AB; School of Pharmacy, University of Otago, Dunedin, 9054, New Zealand., Ashton JC; Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9054, New Zealand., Hawkins BC; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand.
Source: ChemMedChem [ChemMedChem] 2021 Apr 20; Vol. 16 (8), pp. 1308-1315. Date of Electronic Publication: 2021 Jan 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1860-7187
DOI:10.1002/cmdc.202000954