Inhibition of 2-hydroxyglutarate elicits metabolic reprogramming and mutant IDH1 glioma immunity in mice.
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| Title: | Inhibition of 2-hydroxyglutarate elicits metabolic reprogramming and mutant IDH1 glioma immunity in mice. |
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| Authors: | Kadiyala P; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Carney SV; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Gauss JC; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Garcia-Fabiani MB; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Haase S; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Alghamri MS; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Núñez FJ; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Liu Y; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, USA., Yu M; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, USA., Taher A; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Nunez FM; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Li D; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, USA., Edwards MB; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA., Kleer CG; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Appelman H; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Sun Y; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Biostatistics, University of Michigan Medical School, Ann Arbor, Michigan, USA., Zhao L; Department of Biostatistics, University of Michigan Medical School, Ann Arbor, Michigan, USA., Moon JJ; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA., Schwendeman A; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan Medical School, Ann Arbor, Michigan, USA., Lowenstein PR; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan Medical School, Ann Arbor, Michigan, USA., Castro MG; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan Medical School, Ann Arbor, Michigan, USA. |
| Source: | The Journal of clinical investigation [J Clin Invest] 2021 Feb 15; Vol. 131 (4). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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