Effects of mexiletine on hyperexcitability in sporadic amyotrophic lateral sclerosis: Preliminary findings from a small phase II randomized controlled trial.
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| Title: | Effects of mexiletine on hyperexcitability in sporadic amyotrophic lateral sclerosis: Preliminary findings from a small phase II randomized controlled trial. |
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| Authors: | Weiss MD; Department of Neurology, University of Washington, Seattle, Washington, USA., Macklin EA; Department of Medicine, Biostatistics Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., McIlduff CE; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Vucic S; Department of Neurology, Royal Prince Alfred Hospital; and the Brain and Mind Centre, University of Sydney, Sydney, New South Wales, Australia., Wainger BJ; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA., Kiernan MC; Department of Neurology, Royal Prince Alfred Hospital; and the Brain and Mind Centre, University of Sydney, Sydney, New South Wales, Australia., Goutman SA; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA., Goyal NA; Department of Neurology, University of California, Irvine, California, USA., Rutkove SB; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Ladha SS; Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona, USA., Chen IA; Department of Neurology, Medical University of South Carolina, Charleston, South Carolina, USA., Harms MB; Department of Neurology, Columbia University, New York, New York, USA., Brannagan TH; Department of Neurology, Columbia University, New York, New York, USA., Lacomis D; Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Zivkovic S; Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Ma M; Department of Neurology, University of Washington, Seattle, Washington, USA., Wang LH; Department of Neurology, University of Washington, Seattle, Washington, USA., Simmons Z; Department of Neurology, Penn State University, Hershey, Pennsylvania, USA., Rivner MH; Department of Neurology, Augusta University, Augusta, Georgia, USA., Shefner JM; Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona, USA., Cudkowicz ME; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA., Atassi N; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA. |
| Corporate Authors: | Mexiletine-2 ALS Study Group |
| Source: | Muscle & nerve [Muscle Nerve] 2021 Mar; Vol. 63 (3), pp. 371-383. Date of Electronic Publication: 2020 Dec 31. |
| Publication Type: | Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 7803146 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4598 (Electronic) Linking ISSN: 0148639X NLM ISO Abbreviation: Muscle Nerve Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1097-4598 |
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| DOI: | 10.1002/mus.27146 |
