The nucleotide prodrug CERC-913 improves mtDNA content in primary hepatocytes from DGUOK-deficient rats.
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| Title: | The nucleotide prodrug CERC-913 improves mtDNA content in primary hepatocytes from DGUOK-deficient rats. |
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| Authors: | Vanden Avond MA; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Meng H; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Beatka MJ; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Helbling DC; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Prom MJ; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Sutton JL; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Slick RA; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Dimmock DP; Rady Children's Institute for Genomic Medicine, Rady Children's Hospital, San Diego, California, USA., Pertusati F; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK., Serpi M; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK., Pileggi E; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK., Crutcher P; Discovery R&D, Cerecor Inc., Rockville, Maryland, USA., Thomas S; Discovery R&D, Cerecor Inc., Rockville, Maryland, USA., Lawlor MW; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. |
| Source: | Journal of inherited metabolic disease [J Inherit Metab Dis] 2021 Mar; Vol. 44 (2), pp. 492-501. Date of Electronic Publication: 2021 Jan 15. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 7910918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2665 (Electronic) Linking ISSN: 01418955 NLM ISO Abbreviation: J Inherit Metab Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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