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Neuronal delivery of antibodies has therapeutic effects in animal models of botulism.

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Title: Neuronal delivery of antibodies has therapeutic effects in animal models of botulism.
Authors: McNutt PM; Wake Forest School of Medicine, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC 27101, USA.; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA., Vazquez-Cintron EJ; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA.; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.; CytoDel Inc., New York, NY 10016, USA.; City College of City University of New York, NY 10031, USA., Tenezaca L; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.; CytoDel Inc., New York, NY 10016, USA., Ondeck CA; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA., Kelly KE; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA., Mangkhalakhili M; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA., Machamer JB; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA., Angeles CA; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA., Glotfelty EJ; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA., Cika J; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA., Benjumea CH; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA., Whitfield JT; CytoDel Inc., New York, NY 10016, USA., Band PA; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.; CytoDel Inc., New York, NY 10016, USA.; Department of Orthopaedic Surgery, New York University Langone Orthopedic Hospital, New York, NY 10016, USA., Shoemaker CB; Department of Infectious Diseases and Global Health, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA., Ichtchenko K; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA. konstantin.ichtchenko@nyulangone.org.
Source: Science translational medicine [Sci Transl Med] 2021 Jan 06; Vol. 13 (575).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Neuronal delivery of antibodies has therapeutic effects in animal models of botulism.
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  Data: <searchLink fieldCode="AU" term="%22McNutt+PM%22">McNutt PM</searchLink>; Wake Forest School of Medicine, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC 27101, USA.; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA.<br /><searchLink fieldCode="AU" term="%22Vazquez-Cintron+EJ%22">Vazquez-Cintron EJ</searchLink>; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA.; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.; CytoDel Inc., New York, NY 10016, USA.; City College of City University of New York, NY 10031, USA.<br /><searchLink fieldCode="AU" term="%22Tenezaca+L%22">Tenezaca L</searchLink>; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.; CytoDel Inc., New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Ondeck+CA%22">Ondeck CA</searchLink>; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA.<br /><searchLink fieldCode="AU" term="%22Kelly+KE%22">Kelly KE</searchLink>; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA.<br /><searchLink fieldCode="AU" term="%22Mangkhalakhili+M%22">Mangkhalakhili M</searchLink>; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA.<br /><searchLink fieldCode="AU" term="%22Machamer+JB%22">Machamer JB</searchLink>; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA.<br /><searchLink fieldCode="AU" term="%22Angeles+CA%22">Angeles CA</searchLink>; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Glotfelty+EJ%22">Glotfelty EJ</searchLink>; United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA.<br /><searchLink fieldCode="AU" term="%22Cika+J%22">Cika J</searchLink>; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Benjumea+CH%22">Benjumea CH</searchLink>; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Whitfield+JT%22">Whitfield JT</searchLink>; CytoDel Inc., New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Band+PA%22">Band PA</searchLink>; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.; CytoDel Inc., New York, NY 10016, USA.; Department of Orthopaedic Surgery, New York University Langone Orthopedic Hospital, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Shoemaker+CB%22">Shoemaker CB</searchLink>; Department of Infectious Diseases and Global Health, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA.<br /><searchLink fieldCode="AU" term="%22Ichtchenko+K%22">Ichtchenko K</searchLink>; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA. konstantin.ichtchenko@nyulangone.org.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2021 Jan 06; Vol. 13 (575).
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