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Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth.

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Title: Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth.
Authors: Miller KD; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania., Pniewski K; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania., Perry CE; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.; Cell & Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Papp SB; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania., Shaffer JD; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.; Cell & Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Velasco-Silva JN; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.; Biochemistry Department, School of Medicine, University of Utah, Salt Lake City, Utah., Casciano JC; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania., Aramburu TM; Gene Expression and Regulation Program, Wistar Institute, Philadelphia, Pennsylvania., Srikanth YVV; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania., Cassel J; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania., Skordalakes E; Gene Expression and Regulation Program, Wistar Institute, Philadelphia, Pennsylvania., Kossenkov AV; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania., Salvino JM; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania., Schug ZT; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania. zschug@wistar.org.
Source: Cancer research [Cancer Res] 2021 Mar 01; Vol. 81 (5), pp. 1252-1264. Date of Electronic Publication: 2021 Jan 07.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth.
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  Data: <searchLink fieldCode="AU" term="%22Miller+KD%22">Miller KD</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Pniewski+K%22">Pniewski K</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Perry+CE%22">Perry CE</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.; Cell & Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Papp+SB%22">Papp SB</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Shaffer+JD%22">Shaffer JD</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.; Cell & Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Velasco-Silva+JN%22">Velasco-Silva JN</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.; Biochemistry Department, School of Medicine, University of Utah, Salt Lake City, Utah.<br /><searchLink fieldCode="AU" term="%22Casciano+JC%22">Casciano JC</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Aramburu+TM%22">Aramburu TM</searchLink>; Gene Expression and Regulation Program, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Srikanth+YVV%22">Srikanth YVV</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Cassel+J%22">Cassel J</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Skordalakes+E%22">Skordalakes E</searchLink>; Gene Expression and Regulation Program, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Kossenkov+AV%22">Kossenkov AV</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Salvino+JM%22">Salvino JM</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Schug+ZT%22">Schug ZT</searchLink>; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania. zschug@wistar.org.
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  Data: <searchLink fieldCode="JN" term="%222984705R%22">Cancer research</searchLink> [Cancer Res] 2021 Mar 01; Vol. 81 (5), pp. 1252-1264. <i>Date of Electronic Publication: </i>2021 Jan 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2984705R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-7445 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200085472%22">00085472 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Res <i>Subsets: </i>MEDLINE
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