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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.

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Title: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
Authors: Woo XY; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Giordano J; Department of Oncology, University of Turin, Turin, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy., Srivastava A; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Zhao ZM; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Lloyd MW; The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA., de Bruijn R; Netherlands Cancer Institute, Amsterdam, the Netherlands., Suh YS; College of Medicine, Seoul National University, Seoul, Republic of Korea., Patidar R; Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Chen L; Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Scherer S; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Bailey MH; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Human Genetics, University of Utah, Salt Lake City, UT, USA., Yang CH; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Cortes-Sanchez E; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Xi Y; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wang J; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wickramasinghe J; The Wistar Institute, Philadelphia, PA, USA., Kossenkov AV; The Wistar Institute, Philadelphia, PA, USA., Rebecca VW; The Wistar Institute, Philadelphia, PA, USA., Sun H; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Mashl RJ; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Davies SR; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Jeon R; Seven Bridges Genomics, Charlestown, MA, USA., Frech C; Seven Bridges Genomics, Charlestown, MA, USA., Randjelovic J; Seven Bridges Genomics, Charlestown, MA, USA., Rosains J; Seven Bridges Genomics, Charlestown, MA, USA., Galimi F; Department of Oncology, University of Turin, Turin, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy., Bertotti A; Department of Oncology, University of Turin, Turin, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy., Lafferty A; Department of Physiology and Medical Physics, Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., O'Farrell AC; Department of Physiology and Medical Physics, Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Modave E; Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium., Lambrechts D; Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium., Ter Brugge P; Netherlands Cancer Institute, Amsterdam, the Netherlands., Serra V; Vall d´Hebron Institute of Oncology, Barcelona, Spain., Marangoni E; Department of Translational Research, Institut Curie, PSL Research University, Paris, France., El Botty R; Department of Translational Research, Institut Curie, PSL Research University, Paris, France., Kim H; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Kim JI; College of Medicine, Seoul National University, Seoul, Republic of Korea., Yang HK; College of Medicine, Seoul National University, Seoul, Republic of Korea., Lee C; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Precision Medicine Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.; Department of Life Sciences, Ewha Womans University, Seoul, Republic of Korea., Dean DA 2nd; Seven Bridges Genomics, Charlestown, MA, USA., Davis-Dusenbery B; Seven Bridges Genomics, Charlestown, MA, USA., Evrard YA; Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Doroshow JH; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD, USA., Welm AL; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Welm BE; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Surgery, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Lewis MT; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, USA., Fang B; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Roth JA; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Meric-Bernstam F; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Herlyn M; The Wistar Institute, Philadelphia, PA, USA., Davies MA; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Ding L; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Li S; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Govindan R; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Isella C; Department of Oncology, University of Turin, Turin, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy., Moscow JA; Investigational Drug Branch, National Cancer Institute, Bethesda, MD, USA., Trusolino L; Department of Oncology, University of Turin, Turin, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy., Byrne AT; Department of Physiology and Medical Physics, Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Jonkers J; Netherlands Cancer Institute, Amsterdam, the Netherlands., Bult CJ; The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME, USA., Medico E; Department of Oncology, University of Turin, Turin, Italy. enzo.medico@unito.it.; Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy. enzo.medico@unito.it., Chuang JH; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. jeff.chuang@jax.org.
Corporate Authors: PDXNET Consortium, EurOPDX Consortium
Source: Nature genetics [Nat Genet] 2021 Jan; Vol. 53 (1), pp. 86-99. Date of Electronic Publication: 2021 Jan 07.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
An: 33414553
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
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          Dates:
            – D: 01
              M: 01
              Text: 2021 Jan
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 1546-1718
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              Value: 53
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature genetics
              Type: main
ResultId 1