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Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.

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Title: Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Authors: Aschenbrenner AC; Systems Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.; Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Mouktaroudi M; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Krämer B; Department I of Internal Medicine, University Hospital of Bonn (UKB), Bonn, Germany., Oestreich M; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Antonakos N; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Nuesch-Germano M; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Gkizeli K; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Bonaguro L; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Reusch N; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Baßler K; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Saridaki M; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Knoll R; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Pecht T; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Kapellos TS; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Doulou S; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Kröger C; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Herbert M; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Holsten L; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Horne A; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Gemünd ID; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Rovina N; 1st Department of Pulmonary Medicine and Intensive Care Unit, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Agrawal S; West German Genome Center (WGGC), University of Bonn, Bonn, Germany., Dahm K; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., van Uelft M; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Drews A; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany., Lenkeit L; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Bruse N; Department of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Gerretsen J; Department of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Gierlich J; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Becker M; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany., Händler K; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany., Kraut M; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany., Theis H; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany., Mengiste S; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., De Domenico E; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany., Schulte-Schrepping J; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Seep L; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Raabe J; Department I of Internal Medicine, University Hospital of Bonn (UKB), Bonn, Germany., Hoffmeister C; Department I of Internal Medicine, University Hospital of Bonn (UKB), Bonn, Germany., ToVinh M; Department I of Internal Medicine, University Hospital of Bonn (UKB), Bonn, Germany., Keitel V; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Rieke G; Department I of Internal Medicine, University Hospital of Bonn (UKB), Bonn, Germany., Talevi V; Population Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Skowasch D; Department of Internal Medicine II, Section of Pneumology, University Hospital of Bonn (UKB), Bonn, Germany., Aziz NA; Population Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neurology, Faculty of Medicine, University of Bonn, Bonn, Germany., Pickkers P; Department of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., van de Veerdonk FL; Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Netea MG; Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.; Immunology & Metabolism, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Schultze JL; Systems Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Kox M; Department of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Breteler MMB; Population Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), Faculty of Medicine, University of Bonn, Bonn, Germany., Nattermann J; Department I of Internal Medicine, University Hospital of Bonn (UKB), Bonn, Germany.; German Center for Infection Research (DZIF), Bonn, Germany., Koutsoukou A; 1st Department of Pulmonary Medicine and Intensive Care Unit, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Giamarellos-Bourboulis EJ; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Ulas T; Systems Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany. t.ulas@uni-bonn.de.; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany. t.ulas@uni-bonn.de.
Corporate Authors: German COVID-19 Omics Initiative (DeCOI)
Source: Genome medicine [Genome Med] 2021 Jan 13; Vol. 13 (1), pp. 7. Date of Electronic Publication: 2021 Jan 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
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          Name:
            NameFull: Mengiste S
      – PersonEntity:
          Name:
            NameFull: De Domenico E
      – PersonEntity:
          Name:
            NameFull: Schulte-Schrepping J
      – PersonEntity:
          Name:
            NameFull: Seep L
      – PersonEntity:
          Name:
            NameFull: Raabe J
      – PersonEntity:
          Name:
            NameFull: Hoffmeister C
      – PersonEntity:
          Name:
            NameFull: ToVinh M
      – PersonEntity:
          Name:
            NameFull: Keitel V
      – PersonEntity:
          Name:
            NameFull: Rieke G
      – PersonEntity:
          Name:
            NameFull: Talevi V
      – PersonEntity:
          Name:
            NameFull: Skowasch D
      – PersonEntity:
          Name:
            NameFull: Aziz NA
      – PersonEntity:
          Name:
            NameFull: Pickkers P
      – PersonEntity:
          Name:
            NameFull: van de Veerdonk FL
      – PersonEntity:
          Name:
            NameFull: Netea MG
      – PersonEntity:
          Name:
            NameFull: Schultze JL
      – PersonEntity:
          Name:
            NameFull: Kox M
      – PersonEntity:
          Name:
            NameFull: Breteler MMB
      – PersonEntity:
          Name:
            NameFull: Nattermann J
      – PersonEntity:
          Name:
            NameFull: Koutsoukou A
      – PersonEntity:
          Name:
            NameFull: Giamarellos-Bourboulis EJ
      – PersonEntity:
          Name:
            NameFull: Ulas T
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 13
              M: 01
              Text: 2021 Jan 13
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 1756-994X
          Numbering:
            – Type: volume
              Value: 13
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Genome medicine
              Type: main
ResultId 1