Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants.

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Title: Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants.
Authors: Cheng Z; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Bethel CR; Research Services, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA., Thomas PW; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, and the LaMontagne Center for Infectious Disease, University of Texas, Austin, Texas, USA., Shurina BA; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Alao JP; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Thomas CA; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Yang K; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Marshall SH; Research Services, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA., Zhang H; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Sturgill AM; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Kravats AN; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA kravatan@miamioh.edu robert.bonomo@va.gov crowdemw@miamioh.edu., Page RC; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Fast W; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, and the LaMontagne Center for Infectious Disease, University of Texas, Austin, Texas, USA., Bonomo RA; Research Services, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA kravatan@miamioh.edu robert.bonomo@va.gov crowdemw@miamioh.edu.; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Medical Service and GRECC, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.; CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (CASE VA CARES), Cleveland, Ohio, USA., Crowder MW; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA kravatan@miamioh.edu robert.bonomo@va.gov crowdemw@miamioh.edu.
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Mar 18; Vol. 65 (4). Date of Electronic Publication: 2021 Mar 18 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants.
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  Data: <searchLink fieldCode="AU" term="%22Cheng+Z%22">Cheng Z</searchLink>; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Bethel+CR%22">Bethel CR</searchLink>; Research Services, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+PW%22">Thomas PW</searchLink>; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, and the LaMontagne Center for Infectious Disease, University of Texas, Austin, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Shurina+BA%22">Shurina BA</searchLink>; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Alao+JP%22">Alao JP</searchLink>; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+CA%22">Thomas CA</searchLink>; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Yang+K%22">Yang K</searchLink>; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Marshall+SH%22">Marshall SH</searchLink>; Research Services, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Sturgill+AM%22">Sturgill AM</searchLink>; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Kravats+AN%22">Kravats AN</searchLink>; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA kravatan@miamioh.edu robert.bonomo@va.gov crowdemw@miamioh.edu.<br /><searchLink fieldCode="AU" term="%22Page+RC%22">Page RC</searchLink>; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Fast+W%22">Fast W</searchLink>; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, and the LaMontagne Center for Infectious Disease, University of Texas, Austin, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Bonomo+RA%22">Bonomo RA</searchLink>; Research Services, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA kravatan@miamioh.edu robert.bonomo@va.gov crowdemw@miamioh.edu.; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Medical Service and GRECC, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.; CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (CASE VA CARES), Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Crowder+MW%22">Crowder MW</searchLink>; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA kravatan@miamioh.edu robert.bonomo@va.gov crowdemw@miamioh.edu.
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  Data: <searchLink fieldCode="JN" term="%220315061%22">Antimicrobial agents and chemotherapy</searchLink> [Antimicrob Agents Chemother] 2021 Mar 18; Vol. 65 (4). <i>Date of Electronic Publication: </i>2021 Mar 18 (<i>Print Publication: </i>2021).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Microbiology%22">American Society for Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0315061 <i>Publication Model: </i>Electronic-Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-6596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200664804%22">00664804 </searchLink><i>NLM ISO Abbreviation: </i>Antimicrob Agents Chemother <i>Subsets: </i>MEDLINE
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