Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice.
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| Title: | Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice. |
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| Authors: | Ogrodnik M; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Evans SA; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA., Fielder E; Biostatistics Consulting Center, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA., Victorelli S; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Kruger P; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Salmonowicz H; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Weigand BM; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Patel AD; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Pirtskhalava T; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Inman CL; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Johnson KO; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Dickinson SL; Biostatistics Consulting Center, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA., Rocha A; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA., Schafer MJ; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Zhu Y; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Allison DB; Biostatistics Consulting Center, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA., von Zglinicki T; Faculty of Medical Sciences, Biosciences Institute, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK., LeBrasseur NK; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Tchkonia T; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Neretti N; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA., Passos JF; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Kirkland JL; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Jurk D; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA. |
| Source: | Aging cell [Aging Cell] 2021 Feb; Vol. 20 (2), pp. e13296. Date of Electronic Publication: 2021 Jan 20. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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