Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape.
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| Title: | Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape. |
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| Authors: | Ku Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Xie X; Department of Biochemistry and Molecular Biology, Institute for Human Infection and Immunity, Sealy Institute for Vaccine Sciences, Sealy Center for Structural Biology & Molecular Biophysics, Department of Pharmacology & Toxicology, University of Texas Medical Branch, Galveston, TX, 77555, USA., Davidson E; Integral Molecular, Philadelphia, Pennsylvania, PA, 19104, USA., Ye X; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Su H; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Menachery VD; Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX, 77555, USA., Li Y; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Yuan Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Zhang X; Department of Biochemistry and Molecular Biology, Institute for Human Infection and Immunity, Sealy Institute for Vaccine Sciences, Sealy Center for Structural Biology & Molecular Biophysics, Department of Pharmacology & Toxicology, University of Texas Medical Branch, Galveston, TX, 77555, USA., Muruato AE; Department of Biochemistry and Molecular Biology, Institute for Human Infection and Immunity, Sealy Institute for Vaccine Sciences, Sealy Center for Structural Biology & Molecular Biophysics, Department of Pharmacology & Toxicology, University of Texas Medical Branch, Galveston, TX, 77555, USA., I Escuer AG; Integral Molecular, Philadelphia, Pennsylvania, PA, 19104, USA., Tyrell B; Integral Molecular, Philadelphia, Pennsylvania, PA, 19104, USA., Doolan K; Integral Molecular, Philadelphia, Pennsylvania, PA, 19104, USA., Doranz BJ; Integral Molecular, Philadelphia, Pennsylvania, PA, 19104, USA., Wrapp D; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA., Bates PF; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., McLellan JS; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA., Weiss SR; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Zhang N; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA. Ningyan.Zhang@uth.tmc.edu., Shi PY; Department of Biochemistry and Molecular Biology, Institute for Human Infection and Immunity, Sealy Institute for Vaccine Sciences, Sealy Center for Structural Biology & Molecular Biophysics, Department of Pharmacology & Toxicology, University of Texas Medical Branch, Galveston, TX, 77555, USA. peshi@UTMB.EDU., An Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA. Zhiqiang.An@uth.tmc.edu. |
| Source: | Nature communications [Nat Commun] 2021 Jan 20; Vol. 12 (1), pp. 469. Date of Electronic Publication: 2021 Jan 20. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-020-20789-7 |