MAIT cell activation augments adenovirus vector vaccine immunogenicity.

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Title: MAIT cell activation augments adenovirus vector vaccine immunogenicity.
Authors: Provine NM; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK. nicholas.provine@ndm.ox.ac.uk paul.klenerman@ndm.ox.ac.uk., Amini A; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Garner LC; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Spencer AJ; Jenner Institute, University of Oxford, Oxford, UK., Dold C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK., Hutchings C; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK., Silva Reyes L; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK., FitzPatrick MEB; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Chinnakannan S; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK., Oguti B; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK., Raymond M; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK., Ulaszewska M; Jenner Institute, University of Oxford, Oxford, UK., Troise F; Nouscom, SRL, Rome, Italy.; Ceinge Biotechnologie Avanzate, Naples, Italy., Sharpe H; Jenner Institute, University of Oxford, Oxford, UK., Morgan SB; Respiratory Medicine Unit, Nuffield Department of Medicine - Experimental Medicine, University of Oxford, Oxford, UK., Hinks TSC; Respiratory Medicine Unit, Nuffield Department of Medicine - Experimental Medicine, University of Oxford, Oxford, UK., Lambe T; Jenner Institute, University of Oxford, Oxford, UK., Capone S; ReiThera, SRL, Rome, Italy., Folgori A; ReiThera, SRL, Rome, Italy., Barnes E; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Jenner Institute, University of Oxford, Oxford, UK.; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK., Rollier CS; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK., Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK., Klenerman P; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK. nicholas.provine@ndm.ox.ac.uk paul.klenerman@ndm.ox.ac.uk.; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.
Source: Science (New York, N.Y.) [Science] 2021 Jan 29; Vol. 371 (6528), pp. 521-526.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
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  Data: MAIT cell activation augments adenovirus vector vaccine immunogenicity.
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  Data: <searchLink fieldCode="AU" term="%22Provine+NM%22">Provine NM</searchLink>; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK. nicholas.provine@ndm.ox.ac.uk paul.klenerman@ndm.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Amini+A%22">Amini A</searchLink>; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Garner+LC%22">Garner LC</searchLink>; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Spencer+AJ%22">Spencer AJ</searchLink>; Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dold+C%22">Dold C</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hutchings+C%22">Hutchings C</searchLink>; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Silva+Reyes+L%22">Silva Reyes L</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22FitzPatrick+MEB%22">FitzPatrick MEB</searchLink>; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Chinnakannan+S%22">Chinnakannan S</searchLink>; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Oguti+B%22">Oguti B</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Raymond+M%22">Raymond M</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ulaszewska+M%22">Ulaszewska M</searchLink>; Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Troise+F%22">Troise F</searchLink>; Nouscom, SRL, Rome, Italy.; Ceinge Biotechnologie Avanzate, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Sharpe+H%22">Sharpe H</searchLink>; Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Morgan+SB%22">Morgan SB</searchLink>; Respiratory Medicine Unit, Nuffield Department of Medicine - Experimental Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hinks+TSC%22">Hinks TSC</searchLink>; Respiratory Medicine Unit, Nuffield Department of Medicine - Experimental Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lambe+T%22">Lambe T</searchLink>; Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Capone+S%22">Capone S</searchLink>; ReiThera, SRL, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Folgori+A%22">Folgori A</searchLink>; ReiThera, SRL, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Barnes+E%22">Barnes E</searchLink>; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Jenner Institute, University of Oxford, Oxford, UK.; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Rollier+CS%22">Rollier CS</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Pollard+AJ%22">Pollard AJ</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Klenerman+P%22">Klenerman P</searchLink>; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK. nicholas.provine@ndm.ox.ac.uk paul.klenerman@ndm.ox.ac.uk.; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.
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