View in EDS

A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density.

Saved in:
Bibliographic Details
Title: A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density.
Authors: Sinnott-Armstrong N; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Cell Circuits and Epigenomics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Genetics, Stanford University, Stanford 94305 CA, USA., Sousa IS; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Else Kröner-Fresenius-Center for Nutritional Medicine, School of Life Sciences, Technical University of Munich, Freising 85354, Germany., Laber S; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Cell Circuits and Epigenomics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Big Data Institute, University of Oxford, Oxford, UK., Rendina-Ruedy E; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME 04074, USA., Nitter Dankel SE; University of Bergen, Bergen 5020, Norway; Mohn Nutrition Research Laboratory, Department of Clinical Science, University of Bergen, 5020 Bergen, Norway; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, 5021 Bergen, Norway., Ferreira T; Big Data Institute, University of Oxford, Oxford, UK., Mellgren G; University of Bergen, Bergen 5020, Norway; Mohn Nutrition Research Laboratory, Department of Clinical Science, University of Bergen, 5020 Bergen, Norway; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, 5021 Bergen, Norway., Karasik D; Institute for Aging Research, Hebrew SeniorLife and Harvard Medical School, Boston, MA 02131, USA; Faculty of Medicine of the Galilee, Bar-Ilan University, Safed, Israel., Rivas M; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA., Pritchard J; Department of Genetics, Stanford University, Stanford 94305 CA, USA; Department of Biology, Stanford University, Stanford, CA 94305, USA., Guntur AR; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME 04074, USA., Cox RD; Medical Research Council Harwell, Oxfordshire, UK., Lindgren CM; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Big Data Institute, University of Oxford, Oxford, UK., Hauner H; Else Kröner-Fresenius-Center for Nutritional Medicine, School of Life Sciences, Technical University of Munich, Freising 85354, Germany; Institute of Nutritional Medicine, School of Medicine, Technical University of Munich, Freising 85354, Germany; Clinical Cooperation Group 'Nutrigenomics and Type 2 Diabetes' of the German Center of Diabetes Research, Helmholtz Center Munich, Munich 85764, Germany., Sallari R; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Rosen CJ; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME 04074, USA., Hsu YH; Institute for Aging Research, Hebrew SeniorLife and Harvard Medical School, Boston, MA 02131, USA; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02131, USA., Lander ES; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Cell Circuits and Epigenomics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Biology, MIT, Cambridge, MA 02142, USA; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA., Kiel DP; Institute for Aging Research, Hebrew SeniorLife and Harvard Medical School, Boston, MA 02131, USA; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02131, USA., Claussnitzer M; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Cell Circuits and Epigenomics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02131, USA; University of Hohenheim, Institute of Nutritional Science, Stuttgart 70599, Germany. Electronic address: melina@broadinstitute.org.
Source: Cell metabolism [Cell Metab] 2021 Mar 02; Vol. 33 (3), pp. 615-628.e13. Date of Electronic Publication: 2021 Jan 28.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 33513366
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Sinnott-Armstrong+N%22">Sinnott-Armstrong N</searchLink>; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Cell Circuits and Epigenomics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Genetics, Stanford University, Stanford 94305 CA, USA.<br /><searchLink fieldCode="AU" term="%22Sousa+IS%22">Sousa IS</searchLink>; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Else Kröner-Fresenius-Center for Nutritional Medicine, School of Life Sciences, Technical University of Munich, Freising 85354, Germany.<br /><searchLink fieldCode="AU" term="%22Laber+S%22">Laber S</searchLink>; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Cell Circuits and Epigenomics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Big Data Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Rendina-Ruedy+E%22">Rendina-Ruedy E</searchLink>; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME 04074, USA.<br /><searchLink fieldCode="AU" term="%22Nitter+Dankel+SE%22">Nitter Dankel SE</searchLink>; University of Bergen, Bergen 5020, Norway; Mohn Nutrition Research Laboratory, Department of Clinical Science, University of Bergen, 5020 Bergen, Norway; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, 5021 Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Ferreira+T%22">Ferreira T</searchLink>; Big Data Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Mellgren+G%22">Mellgren G</searchLink>; University of Bergen, Bergen 5020, Norway; Mohn Nutrition Research Laboratory, Department of Clinical Science, University of Bergen, 5020 Bergen, Norway; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, 5021 Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Karasik+D%22">Karasik D</searchLink>; Institute for Aging Research, Hebrew SeniorLife and Harvard Medical School, Boston, MA 02131, USA; Faculty of Medicine of the Galilee, Bar-Ilan University, Safed, Israel.<br /><searchLink fieldCode="AU" term="%22Rivas+M%22">Rivas M</searchLink>; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Pritchard+J%22">Pritchard J</searchLink>; Department of Genetics, Stanford University, Stanford 94305 CA, USA; Department of Biology, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Guntur+AR%22">Guntur AR</searchLink>; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME 04074, USA.<br /><searchLink fieldCode="AU" term="%22Cox+RD%22">Cox RD</searchLink>; Medical Research Council Harwell, Oxfordshire, UK.<br /><searchLink fieldCode="AU" term="%22Lindgren+CM%22">Lindgren CM</searchLink>; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Big Data Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hauner+H%22">Hauner H</searchLink>; Else Kröner-Fresenius-Center for Nutritional Medicine, School of Life Sciences, Technical University of Munich, Freising 85354, Germany; Institute of Nutritional Medicine, School of Medicine, Technical University of Munich, Freising 85354, Germany; Clinical Cooperation Group 'Nutrigenomics and Type 2 Diabetes' of the German Center of Diabetes Research, Helmholtz Center Munich, Munich 85764, Germany.<br /><searchLink fieldCode="AU" term="%22Sallari+R%22">Sallari R</searchLink>; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Rosen+CJ%22">Rosen CJ</searchLink>; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME 04074, USA.<br /><searchLink fieldCode="AU" term="%22Hsu+YH%22">Hsu YH</searchLink>; Institute for Aging Research, Hebrew SeniorLife and Harvard Medical School, Boston, MA 02131, USA; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02131, USA.<br /><searchLink fieldCode="AU" term="%22Lander+ES%22">Lander ES</searchLink>; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Cell Circuits and Epigenomics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Biology, MIT, Cambridge, MA 02142, USA; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Kiel+DP%22">Kiel DP</searchLink>; Institute for Aging Research, Hebrew SeniorLife and Harvard Medical School, Boston, MA 02131, USA; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02131, USA.<br /><searchLink fieldCode="AU" term="%22Claussnitzer+M%22">Claussnitzer M</searchLink>; Metabolism Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Cell Circuits and Epigenomics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02131, USA; University of Hohenheim, Institute of Nutritional Science, Stuttgart 70599, Germany. Electronic address: melina@broadinstitute.org.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101233170%22">Cell metabolism</searchLink> [Cell Metab] 2021 Mar 02; Vol. 33 (3), pp. 615-628.e13. <i>Date of Electronic Publication: </i>2021 Jan 28.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101233170 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-7420 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215504131%22">15504131 </searchLink><i>NLM ISO Abbreviation: </i>Cell Metab <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=33513366
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.cmet.2021.01.001
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 615
    Titles:
      – TitleFull: A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Sinnott-Armstrong N
      – PersonEntity:
          Name:
            NameFull: Sousa IS
      – PersonEntity:
          Name:
            NameFull: Laber S
      – PersonEntity:
          Name:
            NameFull: Rendina-Ruedy E
      – PersonEntity:
          Name:
            NameFull: Nitter Dankel SE
      – PersonEntity:
          Name:
            NameFull: Ferreira T
      – PersonEntity:
          Name:
            NameFull: Mellgren G
      – PersonEntity:
          Name:
            NameFull: Karasik D
      – PersonEntity:
          Name:
            NameFull: Rivas M
      – PersonEntity:
          Name:
            NameFull: Pritchard J
      – PersonEntity:
          Name:
            NameFull: Guntur AR
      – PersonEntity:
          Name:
            NameFull: Cox RD
      – PersonEntity:
          Name:
            NameFull: Lindgren CM
      – PersonEntity:
          Name:
            NameFull: Hauner H
      – PersonEntity:
          Name:
            NameFull: Sallari R
      – PersonEntity:
          Name:
            NameFull: Rosen CJ
      – PersonEntity:
          Name:
            NameFull: Hsu YH
      – PersonEntity:
          Name:
            NameFull: Lander ES
      – PersonEntity:
          Name:
            NameFull: Kiel DP
      – PersonEntity:
          Name:
            NameFull: Claussnitzer M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 02
              M: 03
              Text: 2021 Mar 02
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 1932-7420
          Numbering:
            – Type: volume
              Value: 33
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Cell metabolism
              Type: main
ResultId 1