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SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance.

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Title: SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance.
Authors: Fazio M; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States., van Rooijen E; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States., Dang M; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States., van de Hoek G; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States., Ablain J; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States., Mito JK; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Brigham and Women's Hospital, Department of Pathology, Boston, United States., Yang S; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States., Thomas A; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States., Michael J; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States., Fabo T; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States., Modhurima R; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States., Pessina P; Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States., Kaufman CK; Division of Medical Oncology, Department of Medicine, Washington University in Saint Louis, Saint Louis, United States.; Department of Developmental Biology, Washington University in Saint Louis, St. Louis, United States., Zhou Y; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States., White RM; Memorial Sloan Kettering Cancer Center and Weill-Cornell Medical College, New York, United States., Zon LI; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States.
Source: ELife [Elife] 2021 Feb 02; Vol. 10. Date of Electronic Publication: 2021 Feb 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
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  Data: SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance.
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  Data: <searchLink fieldCode="AU" term="%22Fazio+M%22">Fazio M</searchLink>; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States.<br /><searchLink fieldCode="AU" term="%22van+Rooijen+E%22">van Rooijen E</searchLink>; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States.<br /><searchLink fieldCode="AU" term="%22Dang+M%22">Dang M</searchLink>; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States.<br /><searchLink fieldCode="AU" term="%22van+de+Hoek+G%22">van de Hoek G</searchLink>; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.<br /><searchLink fieldCode="AU" term="%22Ablain+J%22">Ablain J</searchLink>; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States.<br /><searchLink fieldCode="AU" term="%22Mito+JK%22">Mito JK</searchLink>; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; 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Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States.<br /><searchLink fieldCode="AU" term="%22Modhurima+R%22">Modhurima R</searchLink>; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States.<br /><searchLink fieldCode="AU" term="%22Pessina+P%22">Pessina P</searchLink>; Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.<br /><searchLink fieldCode="AU" term="%22Kaufman+CK%22">Kaufman CK</searchLink>; Division of Medical Oncology, Department of Medicine, Washington University in Saint Louis, Saint Louis, United States.; Department of Developmental Biology, Washington University in Saint Louis, St. Louis, United States.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, United States.<br /><searchLink fieldCode="AU" term="%22White+RM%22">White RM</searchLink>; Memorial Sloan Kettering Cancer Center and Weill-Cornell Medical College, New York, United States.<br /><searchLink fieldCode="AU" term="%22Zon+LI%22">Zon LI</searchLink>; Howard Hughes Medical Institute, Stem Cell Program and the Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, United States.; 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