Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness.

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Title: Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness.
Authors: Bonneau M; Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK. bonneau.mb@gmail.com., Sullivan STO; Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Gonzalez-Lozano MA; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands., Baxter P; Centre for Discovery Brain Sciences, Hugh Robson Building, The University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute, Edinburgh Medical School, The University of Edinburgh, Edinburgh, UK., Gautier P; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Marchisella E; Sylics Synaptologics BV, Amsterdam, The Netherlands., Hardingham NR; School of Biosciences, Museum Avenue, Cardiff University, Cardiff, UK., Chesters RA; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Torrance H; Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Howard DM; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Division of Psychiatry, Kennedy Tower, The University of Edinburgh, Edinburgh, UK., Jansen MA; Edinburgh Preclinical Imaging, The Chancellor's Building, The University of Edinburgh, Edinburgh, UK., McMillan M; Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK., Singh Y; Centre for Genomics and Transcriptomics, Paul-Ehrlich-Straße 23, Tübingen, Germany., Didier M; Translational Sciences at Sanofi, Chilly-Mazarin, France., Koopmans F; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands., Semple CA; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., McIntosh AM; Division of Psychiatry, Kennedy Tower, The University of Edinburgh, Edinburgh, UK., Volkmer H; Department of Molecular Biology, NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany., Loos M; Sylics Synaptologics BV, Amsterdam, The Netherlands., Fox K; School of Biosciences, Museum Avenue, Cardiff University, Cardiff, UK., Hardingham GE; Centre for Discovery Brain Sciences, Hugh Robson Building, The University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute, Edinburgh Medical School, The University of Edinburgh, Edinburgh, UK., Vernon AC; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK., Porteous DJ; Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Smit AB; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands., Price DJ; Centre for Discovery Brain Sciences, Hugh Robson Building, The University of Edinburgh, Edinburgh, UK., Kirsty Millar J; Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK.
Source: Translational psychiatry [Transl Psychiatry] 2021 Feb 19; Vol. 11 (1), pp. 135. Date of Electronic Publication: 2021 Feb 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
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  Data: Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness.
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  Data: <searchLink fieldCode="AU" term="%22Bonneau+M%22">Bonneau M</searchLink>; Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK. bonneau.mb@gmail.com.<br /><searchLink fieldCode="AU" term="%22Sullivan+STO%22">Sullivan STO</searchLink>; Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Lozano+MA%22">Gonzalez-Lozano MA</searchLink>; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Baxter+P%22">Baxter P</searchLink>; Centre for Discovery Brain Sciences, Hugh Robson Building, The University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute, Edinburgh Medical School, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Gautier+P%22">Gautier P</searchLink>; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Marchisella+E%22">Marchisella E</searchLink>; Sylics Synaptologics BV, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hardingham+NR%22">Hardingham NR</searchLink>; School of Biosciences, Museum Avenue, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Chesters+RA%22">Chesters RA</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Torrance+H%22">Torrance H</searchLink>; Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Howard+DM%22">Howard DM</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Division of Psychiatry, Kennedy Tower, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Jansen+MA%22">Jansen MA</searchLink>; Edinburgh Preclinical Imaging, The Chancellor's Building, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22McMillan+M%22">McMillan M</searchLink>; Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Singh+Y%22">Singh Y</searchLink>; Centre for Genomics and Transcriptomics, Paul-Ehrlich-Straße 23, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Didier+M%22">Didier M</searchLink>; Translational Sciences at Sanofi, Chilly-Mazarin, France.<br /><searchLink fieldCode="AU" term="%22Koopmans+F%22">Koopmans F</searchLink>; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Semple+CA%22">Semple CA</searchLink>; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22McIntosh+AM%22">McIntosh AM</searchLink>; Division of Psychiatry, Kennedy Tower, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Volkmer+H%22">Volkmer H</searchLink>; Department of Molecular Biology, NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.<br /><searchLink fieldCode="AU" term="%22Loos+M%22">Loos M</searchLink>; Sylics Synaptologics BV, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Fox+K%22">Fox K</searchLink>; School of Biosciences, Museum Avenue, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Hardingham+GE%22">Hardingham GE</searchLink>; Centre for Discovery Brain Sciences, Hugh Robson Building, The University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute, Edinburgh Medical School, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Vernon+AC%22">Vernon AC</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Porteous+DJ%22">Porteous DJ</searchLink>; Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Smit+AB%22">Smit AB</searchLink>; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Price+DJ%22">Price DJ</searchLink>; Centre for Discovery Brain Sciences, Hugh Robson Building, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Kirsty+Millar+J%22">Kirsty Millar J</searchLink>; Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK.
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