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SARS-CoV-2 B.1.1.7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies.

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Title: SARS-CoV-2 B.1.1.7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies.
Authors: Collier DA; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; Division of Infection and Immunity, University College London, London, UK., De Marco A; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Ferreira IATM; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Meng B; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Datir R; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; Division of Infection and Immunity, University College London, London, UK., Walls AC; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Kemp S SA; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; Division of Infection and Immunity, University College London, London, UK., Bassi J; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Pinto D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Fregni CS; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Bianchi S; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Bowen J; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Culap K; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Jaconi S; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Cameroni E; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Snell G; Vir Biotechnology, San Francisco, CA 94158, USA., Pizzuto MS; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Pellanda AF; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland., Garzoni C; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland., Riva A; Division of Infectious Diseases, Luigi Sacco Hospital, University of Milan, Milan, Italy., Elmer A; NIHR Cambridge Clinical Research Facility, Cambridge, UK., Kingston N; NIHR Bioresource, Cambridge, UK., Graves B; NIHR Bioresource, Cambridge, UK., McCoy LE; Division of Infection and Immunity, University College London, London, UK., Smith KG; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Bradley JR; Department of Medicine, University of Cambridge, Cambridge, UK.; NIHR Bioresource, Cambridge, UK., Temperton N; University of Kent, Canturbury, UK., Ceron-Gutierrez L L; Department of Clinical Biochemistry and Immunology, Addenbrookes Hospital, UK., Barcenas-Morales G; Department of Clinical Biochemistry and Immunology, Addenbrookes Hospital, UK.; Laboratorio de Inmunologia, S-Cuautitlán, UNAM, Mexico., Harvey W; Institute of Biodiversity, University of Glasgow, Glasgow, UK., Virgin HW; Vir Biotechnology, San Francisco, CA 94158, USA., Lanzavecchia A; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Piccoli L; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Doffinger R; Department of Clinical Biochemistry and Immunology, Addenbrookes Hospital, UK., Wills M; Department of Medicine, University of Cambridge, Cambridge, UK., Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Corti D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Gupta RK; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; University of KwaZulu Natal, Durban, South Africa.; Africa Health Research Institute, Durban, South Africa.; Department of Infectious Diseases, Cambridge University Hospitals NHS Trust, Cambridge UK.
Corporate Authors: CITIID-NIHR BioResource COVID-19 Collaboration, COVID-19 Genomics UK (COG-UK) consortium
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2021 Feb 15. Date of Electronic Publication: 2021 Feb 15.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: SARS-CoV-2 B.1.1.7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies.
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  Data: <searchLink fieldCode="AU" term="%22Collier+DA%22">Collier DA</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; Division of Infection and Immunity, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22De+Marco+A%22">De Marco A</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ferreira+IATM%22">Ferreira IATM</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Meng+B%22">Meng B</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Datir+R%22">Datir R</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; Division of Infection and Immunity, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Walls+AC%22">Walls AC</searchLink>; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.<br /><searchLink fieldCode="AU" term="%22Kemp+S+SA%22">Kemp S SA</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; Division of Infection and Immunity, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bassi+J%22">Bassi J</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pinto+D%22">Pinto D</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Fregni+CS%22">Fregni CS</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bianchi+S%22">Bianchi S</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tortorici+MA%22">Tortorici MA</searchLink>; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.<br /><searchLink fieldCode="AU" term="%22Bowen+J%22">Bowen J</searchLink>; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.<br /><searchLink fieldCode="AU" term="%22Culap+K%22">Culap K</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jaconi+S%22">Jaconi S</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cameroni+E%22">Cameroni E</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Snell+G%22">Snell G</searchLink>; Vir Biotechnology, San Francisco, CA 94158, USA.<br /><searchLink fieldCode="AU" term="%22Pizzuto+MS%22">Pizzuto MS</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pellanda+AF%22">Pellanda AF</searchLink>; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Garzoni+C%22">Garzoni C</searchLink>; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Riva+A%22">Riva A</searchLink>; Division of Infectious Diseases, Luigi Sacco Hospital, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Elmer+A%22">Elmer A</searchLink>; NIHR Cambridge Clinical Research Facility, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kingston+N%22">Kingston N</searchLink>; NIHR Bioresource, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Graves+B%22">Graves B</searchLink>; NIHR Bioresource, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22McCoy+LE%22">McCoy LE</searchLink>; Division of Infection and Immunity, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Smith+KG%22">Smith KG</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Bradley+JR%22">Bradley JR</searchLink>; Department of Medicine, University of Cambridge, Cambridge, UK.; NIHR Bioresource, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Temperton+N%22">Temperton N</searchLink>; University of Kent, Canturbury, UK.<br /><searchLink fieldCode="AU" term="%22Ceron-Gutierrez+L+L%22">Ceron-Gutierrez L L</searchLink>; Department of Clinical Biochemistry and Immunology, Addenbrookes Hospital, UK.<br /><searchLink fieldCode="AU" term="%22Barcenas-Morales+G%22">Barcenas-Morales G</searchLink>; Department of Clinical Biochemistry and Immunology, Addenbrookes Hospital, UK.; Laboratorio de Inmunologia, S-Cuautitlán, UNAM, Mexico.<br /><searchLink fieldCode="AU" term="%22Harvey+W%22">Harvey W</searchLink>; Institute of Biodiversity, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Virgin+HW%22">Virgin HW</searchLink>; Vir Biotechnology, San Francisco, CA 94158, USA.<br /><searchLink fieldCode="AU" term="%22Lanzavecchia+A%22">Lanzavecchia A</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Piccoli+L%22">Piccoli L</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Doffinger+R%22">Doffinger R</searchLink>; Department of Clinical Biochemistry and Immunology, Addenbrookes Hospital, UK.<br /><searchLink fieldCode="AU" term="%22Wills+M%22">Wills M</searchLink>; Department of Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Veesler+D%22">Veesler D</searchLink>; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.<br /><searchLink fieldCode="AU" term="%22Corti+D%22">Corti D</searchLink>; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gupta+RK%22">Gupta RK</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; University of KwaZulu Natal, Durban, South Africa.; Africa Health Research Institute, Durban, South Africa.; Department of Infectious Diseases, Cambridge University Hospitals NHS Trust, Cambridge UK.
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