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Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages.

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Title: Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages.
Authors: Sharif O; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria omar.sharif@meduniwien.ac.at sylvia.knapp@meduniwien.ac.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria., Brunner JS; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria., Korosec A; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Martins R; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Jais A; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Snijder B; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Vogel A; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria., Caldera M; Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria., Hladik A; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Lakovits K; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Saluzzo S; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Boehm B; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Gorki AD; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Mesteri I; Institute of Pathology, Überlingen, Germany., Lindroos-Christensen J; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Tillmann K; Center of Biomedical Research, Medical University of Vienna, Vienna, Austria., Stoiber D; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.; Division of Pharmacology, Department of Pharmacology, Physiology and Microbiology, Karl Landsteiner University of Health Sciences, Krems, Austria., Menche J; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria.; Faculty of Mathematics, University of Vienna, Vienna, Austria., Schabbauer G; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria., Bilban M; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Superti-Furga G; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria., Esterbauer H; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Knapp S; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria omar.sharif@meduniwien.ac.at sylvia.knapp@meduniwien.ac.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Source: Diabetes [Diabetes] 2021 Sep; Vol. 70 (9), pp. 2042-2057. Date of Electronic Publication: 2021 Feb 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE
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  Data: Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages.
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  Data: <searchLink fieldCode="AU" term="%22Sharif+O%22">Sharif O</searchLink>; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria omar.sharif@meduniwien.ac.at sylvia.knapp@meduniwien.ac.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Brunner+JS%22">Brunner JS</searchLink>; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Korosec+A%22">Korosec A</searchLink>; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Martins+R%22">Martins R</searchLink>; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Jais+A%22">Jais A</searchLink>; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Snijder+B%22">Snijder B</searchLink>; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Vogel+A%22">Vogel A</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Caldera+M%22">Caldera M</searchLink>; Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hladik+A%22">Hladik A</searchLink>; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Lakovits+K%22">Lakovits K</searchLink>; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Saluzzo+S%22">Saluzzo S</searchLink>; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Boehm+B%22">Boehm B</searchLink>; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Gorki+AD%22">Gorki AD</searchLink>; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Mesteri+I%22">Mesteri I</searchLink>; Institute of Pathology, Überlingen, Germany.<br /><searchLink fieldCode="AU" term="%22Lindroos-Christensen+J%22">Lindroos-Christensen J</searchLink>; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Tillmann+K%22">Tillmann K</searchLink>; Center of Biomedical Research, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Stoiber+D%22">Stoiber D</searchLink>; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.; Division of Pharmacology, Department of Pharmacology, Physiology and Microbiology, Karl Landsteiner University of Health Sciences, Krems, Austria.<br /><searchLink fieldCode="AU" term="%22Menche+J%22">Menche J</searchLink>; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Vienna, Austria.; Faculty of Mathematics, University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Schabbauer+G%22">Schabbauer G</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Bilban+M%22">Bilban M</searchLink>; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Superti-Furga+G%22">Superti-Furga G</searchLink>; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Esterbauer+H%22">Esterbauer H</searchLink>; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Knapp+S%22">Knapp S</searchLink>; Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria omar.sharif@meduniwien.ac.at sylvia.knapp@meduniwien.ac.; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
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  Data: <searchLink fieldCode="JN" term="%220372763%22">Diabetes</searchLink> [Diabetes] 2021 Sep; Vol. 70 (9), pp. 2042-2057. <i>Date of Electronic Publication: </i>2021 Feb 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Diabetes+Association%22">American Diabetes Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372763 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1939-327X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200121797%22">00121797 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes <i>Subsets: </i>MEDLINE
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