View in EDS PDF Full Text

Bromelain inhibits SARS-CoV-2 infection via targeting ACE-2, TMPRSS2, and spike protein.

Saved in:
Bibliographic Details
Title: Bromelain inhibits SARS-CoV-2 infection via targeting ACE-2, TMPRSS2, and spike protein.
Authors: Sagar S; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA., Rathinavel AK; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA., Lutz WE; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA., Struble LR; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA., Khurana S; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), FDA, Silver Spring, Maryland, USA., Schnaubelt AT; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA., Mishra NK; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA., Guda C; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA., Palermo NY; Computational Chemistry Core, University of Nebraska Medical Center, Omaha, Nebraska, USA., Broadhurst MJ; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA., Hoffmann T; Advanced Light and Electron Microscopy, Centre for Biological Threats and Special Pathogens 4 (ZBS 4), Robert Koch Institute, Berlin, Germany., Bayles KW; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA., Reid SPM; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA., Borgstahl GEO; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA., Radhakrishnan P; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Source: Clinical and translational medicine [Clin Transl Med] 2021 Feb; Vol. 11 (2), pp. e281.
Publication Type: Letter
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Print ISSN: 2001-1326 (Print) Linking ISSN: 20011326 NLM ISO Abbreviation: Clin Transl Med
Database: MEDLINE Ultimate
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 33635001
AccessLevel: 2
PubType: Editorial & Opinion
PubTypeId: editorialOpinion
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Bromelain inhibits SARS-CoV-2 infection via targeting ACE-2, TMPRSS2, and spike protein.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Sagar+S%22">Sagar S</searchLink>; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Rathinavel+AK%22">Rathinavel AK</searchLink>; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Lutz+WE%22">Lutz WE</searchLink>; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Struble+LR%22">Struble LR</searchLink>; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Khurana+S%22">Khurana S</searchLink>; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), FDA, Silver Spring, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Schnaubelt+AT%22">Schnaubelt AT</searchLink>; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Mishra+NK%22">Mishra NK</searchLink>; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Guda+C%22">Guda C</searchLink>; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Palermo+NY%22">Palermo NY</searchLink>; Computational Chemistry Core, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Broadhurst+MJ%22">Broadhurst MJ</searchLink>; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Hoffmann+T%22">Hoffmann T</searchLink>; Advanced Light and Electron Microscopy, Centre for Biological Threats and Special Pathogens 4 (ZBS 4), Robert Koch Institute, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Bayles+KW%22">Bayles KW</searchLink>; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Reid+SPM%22">Reid SPM</searchLink>; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Borgstahl+GEO%22">Borgstahl GEO</searchLink>; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Radhakrishnan+P%22">Radhakrishnan P</searchLink>; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101597971%22">Clinical and translational medicine</searchLink> [Clin Transl Med] 2021 Feb; Vol. 11 (2), pp. e281.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Letter
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101597971 <i>Publication Model: </i>Print <i>Cited Medium: </i>Print <i>ISSN: </i>2001-1326 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220011326%22">20011326 </searchLink><i>NLM ISO Abbreviation: </i>Clin Transl Med
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=33635001
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/ctm2.281
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e281
    Titles:
      – TitleFull: Bromelain inhibits SARS-CoV-2 infection via targeting ACE-2, TMPRSS2, and spike protein.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Sagar S
      – PersonEntity:
          Name:
            NameFull: Rathinavel AK
      – PersonEntity:
          Name:
            NameFull: Lutz WE
      – PersonEntity:
          Name:
            NameFull: Struble LR
      – PersonEntity:
          Name:
            NameFull: Khurana S
      – PersonEntity:
          Name:
            NameFull: Schnaubelt AT
      – PersonEntity:
          Name:
            NameFull: Mishra NK
      – PersonEntity:
          Name:
            NameFull: Guda C
      – PersonEntity:
          Name:
            NameFull: Palermo NY
      – PersonEntity:
          Name:
            NameFull: Broadhurst MJ
      – PersonEntity:
          Name:
            NameFull: Hoffmann T
      – PersonEntity:
          Name:
            NameFull: Bayles KW
      – PersonEntity:
          Name:
            NameFull: Reid SPM
      – PersonEntity:
          Name:
            NameFull: Borgstahl GEO
      – PersonEntity:
          Name:
            NameFull: Radhakrishnan P
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: 2021 Feb
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-print
              Value: 2001-1326
          Numbering:
            – Type: volume
              Value: 11
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Clinical and translational medicine
              Type: main
ResultId 1