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Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity.

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Title: Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity.
Authors: Sorek M; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.; The Edmond and Lily Center for Brain Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel., Oweis W; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel., Nissim-Rafinia M; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel., Maman M; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel., Simon S; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel., Hession CC; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Adiconis X; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Simmons SK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sanjana NE; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; New York Genome Center and Department of Biology, New York University, New York, NY, USA., Shi X; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lu C; New York Genome Center and Department of Biology, New York University, New York, NY, USA., Pan JQ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Xu X; Department of Neurology and Stroke Center, The First Affiliated Hospital, Jinan University, 613 Huangpu Avenue West, Guangzhou, 510632, Guangdong, China.; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore., Pouladi MA; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.; Department of Physiology, National University of Singapore, Singapore, 117597, Singapore.; British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, V5Z 4H4, Canada., Ellerby LM; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA., Zhang F; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Levin JZ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Meshorer E; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel. eran.meshorer@mail.huji.ac.il.; The Edmond and Lily Center for Brain Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel. eran.meshorer@mail.huji.ac.il.
Source: Genome biology [Genome Biol] 2021 Mar 04; Vol. 22 (1), pp. 73. Date of Electronic Publication: 2021 Mar 04.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity.
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  Data: <searchLink fieldCode="AU" term="%22Sorek+M%22">Sorek M</searchLink>; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.; The Edmond and Lily Center for Brain Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Oweis+W%22">Oweis W</searchLink>; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Nissim-Rafinia+M%22">Nissim-Rafinia M</searchLink>; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Maman+M%22">Maman M</searchLink>; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Simon+S%22">Simon S</searchLink>; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Hession+CC%22">Hession CC</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Adiconis+X%22">Adiconis X</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Simmons+SK%22">Simmons SK</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sanjana+NE%22">Sanjana NE</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; New York Genome Center and Department of Biology, New York University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shi+X%22">Shi X</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lu+C%22">Lu C</searchLink>; New York Genome Center and Department of Biology, New York University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pan+JQ%22">Pan JQ</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; Department of Neurology and Stroke Center, The First Affiliated Hospital, Jinan University, 613 Huangpu Avenue West, Guangzhou, 510632, Guangdong, China.; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.<br /><searchLink fieldCode="AU" term="%22Pouladi+MA%22">Pouladi MA</searchLink>; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.; Department of Physiology, National University of Singapore, Singapore, 117597, Singapore.; British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, V5Z 4H4, Canada.<br /><searchLink fieldCode="AU" term="%22Ellerby+LM%22">Ellerby LM</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Levin+JZ%22">Levin JZ</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Meshorer+E%22">Meshorer E</searchLink>; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel. eran.meshorer@mail.huji.ac.il.; The Edmond and Lily Center for Brain Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel. eran.meshorer@mail.huji.ac.il.
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  Data: <searchLink fieldCode="JN" term="%22100960660%22">Genome biology</searchLink> [Genome Biol] 2021 Mar 04; Vol. 22 (1), pp. 73. <i>Date of Electronic Publication: </i>2021 Mar 04.
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